Classic psychedelic and cannabis use among U.S. cancer survivors aged ≥ 50 years: nationally representative estimates by cancer type/site.
To examine the prevalence of lifetime ("ever") cannabis and classic psychedelic use, and their co-use among U.S. adults aged ≥ 50 years with versus without a...
Characterizing public comments via Regulations.gov in response to proposed cannabis rescheduling in the United States.
The United States Drug Enforcement Administration's (DEA) proposed rescheduling of cannabis from Schedule I to Schedule III under the Controlled Substances A...
Cannabis use patterns in first episode psychosis and schizophrenia: A scoping review and case series.
Cannabis use is associated with psychosis development and symptom relapse in persons with schizophrenia spectrum disorders (SCZ). As U.S. states legalize can...
Cannabinoids and cognition in Parkinson’s disease: Insights from animal models and emerging clinical evidence.
Parkinson's disease (PD) is a progressive, multisystem neurodegenerative disorder characterized not only by motor impairments but also by a broad spectrum of...
Tetrahydrocoptisine alleviates postoperative delirium with sleep disturbances by modulating the TH/NLRP3 Inflammasome pathway.
Postoperative delirium (POD) accompanied by sleep disturbances (SD) represents a significant concern in perioperative neurocognitive health. Emerging evidenc...
Local therapeutic strategies for neurocutaneous dysesthesia: from capsaicin to cannabinoids.
Neurocutaneous dysesthesia (ND) is characterized by abnormal skin sensations such as pruritus or burning without an underlying skin condition. It is caused b...
The quality and scope of health information on online drug platforms: a topic modelling and expert evaluation study of a Polish-language forum.
Determining health information quality on online drug platforms is crucial for revealing and shaping substance use practices. The study aims to assess the sc...
Phenome-Wide Associations of Polygenic Scores for Schizophrenia and Major Depression in 100,000 Chinese Adults.
China faces significant mental health challenges, with unique associations between mental disorders and other traits observed in its population. Based on sum...
Molecular Basis Underlying Changes of Brain Entropy and Couplings in Late-life Depression.
Late-life depression (LLD) with high prevalence accelerates cognitive impairment and becomes a risk factor for dementia, yet the pathogenesis of LLD is still...
Envisioning Cannabinoid CB1 Receptor Biased Signaling as a Therapeutic Target for Schizophrenia.
The relationship between the endocannabinoid system and the emergence and treatment of schizophrenia-related symptoms continues to be a topic of significant ...