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Hemp-Derived Extracellular Vesicles: A Novel Frontier in Nanomedicine and Therapeutics.
While mammalian-derived extracellular vesicles (EVs) face significant challenges in clinical translation due to scalability, cost, and safety, plant-derived ...
Polycyclic aromatic hydrocarbons and cannabinoids in secondhand cannabis smoke.
The legalization of cannabis is exposing more people to secondhand smoke (SHS) generated during cannabis use. Given the serious health effects caused by toba...
Cannabigerol induces endoplasmic reticulum stress-mediated apoptosis and ferroptosis via the IRE1α-XBP1 axis in human pancreatic cancer cells.
Cannabigerol (CBG), a non-psychoactive phytocannabinoid derived from Cannabis sativa, has attracted increasing attention owing to its antibiotic, anti-inflam...
Associations of cannabis use, other substances, and lifestyle choices on anxiety in medical cannabis patients across 45 days.
Previous research has shown medical cannabis (MC) to help reduce anxiety for some individuals, although most studies show trends using cross-sectional design...
Metformin reverses oxandrolone-induced anxiety-like behavior and amygdalar neurochemical dysregulation in male rats.
Oxandrolone, a synthetic anabolic androgenic steroid, is widely used for its muscle-building effects but has been associated with anxiety and mood disturbanc...
Parental sociodemographic profiles in relation to mental health, cannabis use motives, and cannabis use behaviors among a sample of US young adult parents.
Although past-month cannabis use has increased among US parents, little work has identified factors associated with parental use. We analyzed 2023 survey dat...
Cannabidiol-Loaded Smart Hydrogels for Advanced Wound Healing: Drug Delivery Innovations and Therapeutic Perspectives
Chronic wounds pose a significant healthcare challenge worldwide, requiring innovative treatments. Cannabidiol wound healing shows promise due to its anti-inflammatory and regenerative properties. Smart hydrogels offer advanced drug delivery platforms to…
Differential Effects of Oleoyl Serine and HU-910 on Anxiety and Depression in WKY Rats
The endocannabinoid system depression anxiety connection is actively researched for therapeutic potential. This study investigates Oleoyl Serine and HU-910 effects on anxiety and depression behaviors in WKY rats. Results show sex-specific anxiolytic and…
Effect of cannabinol, tetrahydrocannabivarin and cannabidiol on voluntary alcohol consumption.
Previous studies have demonstrated that the endocannabinoid system plays a significant role in the development of alcohol use disorder (AUD), and CB1 recepto...
The Dual Roles of Natural Cannabidiol in Combating Oxidative Stress and Inflammation: A Potential Intestinal Guardian
Cannabidiol antioxidant intestinal protection is gaining attention for its therapeutic potential in gut health. CBD helps combat oxidative stress and inflammation in the gastrointestinal tract. This natural compound supports intestinal barrier integrity…