Metabolic dysfunction-associated fatty liver disease (MAFLD), recently redefined from non-alcoholic fatty liver disease (NAFLD), highlights the central role …
Cannabinoids in Combination with Conventional Breast Cancer Therapies: Mechanistic Insights and the Gap to Clinical Translation.
Current treatments for breast cancer (BC) include surgery, radiation, chemotherapy, targeted therapy, hormonal therapy, and immunotherapy. However, adverse e…
Pharmacokinetic and pharmacodynamic properties of cannabigerol in male mice.
Cannabigerol (CBG) is a nonintoxicating phytocannabinoid gaining popularity as a self-medication for anxiety and other conditions; however, its pharmacologic…
Cannabidiol in Epilepsy: Restoring Locomotion and Seizure Control.
Epilepsy remains a global challenge, with about one-third of affected patients being resistant to treatment. Seizures and motor abnormalities characterized b…
Personalized resilience: how individual variability in brain-immune responses to stress influences the development of anxiety disorders.
Stress exposure has increased significantly, contributing to higher rates of anxiety, depression, and post-traumatic stress disorder. However, individual res…
Spontaneous Pneumomediastinum and Cannabinoid Hyperemesis Syndrome: A Case Report and Literature Review.
We report the case of an 18-year-old man with a six-month history of chronic marijuana use who developed spontaneous pneumomediastinum (SPM) following multip…
Cannabis Hyperemesis Syndrome: A Psychiatric Approach.
Cannabis hyperemesis syndrome (CHS) is a rare complication presenting with recurrent episodes of intractable nausea, vomiting, and abdominal pain that manife…
Alcohol as a Novel Trigger for Cannabis Hyperemesis Syndrome.
Cannabis hyperemesis syndrome (CHS) is a paradoxical condition occurring in chronic cannabis users, characterized by cyclic nausea, vomiting, and abdominal p…
Marijuana Use and Its Impact on Outpatient Anesthesia.
Cannabis is one of the most common psychoactive substances used worldwide, and its use is increasing. Modern products vary widely in tetrahydrocannabinol (TH…