Cannabinoids and cognition in Parkinson’s disease: Insights from animal models and emerging clinical evidence.
Cannabinoids and cognition in Parkinson's disease are increasingly studied due to the endocannabinoid system's role in neural circuits affected by PD. Animal models show promising neuroprotective and cognition-preserving effects of cannabinoids. However,…
Enhancing Endocannabinoid System for Residual Disease in MS
This clinical study endocannabinoid system approach addresses residual disease in relapse-free multiple sclerosis patients. High-efficacy therapies reduce relapses but symptoms persist. Enhancing the endocannabinoid system offers new treatment insights.
Targeting the LPI/GPR55 Axis in MAFLD and MASH: Novel Insights, Therapeutic Strategies and Future Directions.
The LPI GPR55 receptor axis plays a crucial role in metabolic dysfunction-associated fatty liver disease (MAFLD). This pathway contributes to liver fat accumulation, inflammation, and fibrosis. Understanding this axis offers novel insights into potential…
Cannabinoids in Combination with Conventional Breast Cancer Therapies: Mechanistic Insights and the Gap to Clinical Translation.
This review highlights cannabinoid anti-tumor effects breast cancer research and its potential to enhance conventional therapies. It emphasizes the gap between preclinical findings and clinical translation. Understanding these effects is crucial for…
Pharmacokinetic and Pharmacodynamic Properties of Cannabigerol in Male Mice
This study investigates the pharmacokinetic properties of cannabigerol in male mice, highlighting its brain penetration and metabolite accumulation. Findings reveal unexpected anxiogenic effects at peak brain concentrations. Understanding these…
Personalized Resilience: Variability in Brain-Immune Stress Responses
Brain-immune responses to stress vary significantly among individuals, influencing anxiety disorder development. This variability affects HPA axis regulation and immune function. Understanding these responses is key to personalized resilience strategies.
Spontaneous Pneumomediastinum and Cannabinoid Hyperemesis Syndrome: A Case Report and Literature Review
This case report highlights spontaneous pneumomediastinum as a rare complication of cannabinoid hyperemesis syndrome. An 18-year-old chronic cannabis user developed spontaneous pneumomediastinum following severe vomiting. Understanding this complication…
Cannabis Hyperemesis Syndrome: A Psychiatric Approach
Cannabis hyperemesis syndrome psychiatric risk is a critical consideration in patients with chronic cannabis use presenting with cyclical vomiting. This syndrome often poses diagnostic challenges in psychiatric settings due to overlapping symptoms. Early…
Alcohol as a Novel Trigger for Cannabis Hyperemesis Syndrome
Alcohol cannabis hyperemesis trigger is emerging as a novel factor in cannabis hyperemesis syndrome (CHS). This condition affects chronic cannabis users with cyclic nausea and vomiting. Understanding alcohol's role may improve clinical counseling and…
Marijuana Use and Its Impact on Outpatient Anesthesia
Anesthesia progress clinical study marijuana use reveals important implications for outpatient anesthesia. Cannabis affects multiple organ systems and alters anesthetic requirements. Understanding these effects is crucial for safe perioperative care.