Romantic relationships are important contexts for substance use and emotional well-being. We tested the hypotheses that (i) genetic predispositions for alcoh…
The Effects of Extended Cannabis Abstinence in Comorbid Posttraumatic Stress Disorder and Cannabis Use Disorder.
CED Clinical Relevance #56Monitored Relevance Early-stage or contextual signal requiring further evidence before action. 🔬 Evidence Watch | CED Clinic PtsdCannabis Use DisorderAbstinenceDual DiagnosisMental Health JournalThe Journal of clinical psychiatryStudy TypeClinical StudyPopulationHuman participants Why This MattersThis...
The effect of cannabis use on the time course of positive and negative affect in the daily life of youth.
CED Clinical Relevance #56Monitored Relevance Early-stage or contextual signal requiring further evidence before action. 🔬 Evidence Watch | CED Clinic YouthMoodReal-World EvidenceAdolescentsEmotional Regulation JournalPsychopharmacologyStudy TypeClinical StudyPopulationHuman participants Why This MattersThis study addresses a critical gap in...
Using machine learning to identify unique predictors of alcohol and cannabis impaired driving.
Alcohol- and cannabis-impaired driving remain major public health concerns, particularly among young adults. Although prior studies have identified numerous …
Therapeutically Motivated Cannabis Use for Anxiety: Daily and Longitudinal Reductions Vary Between Flower and Edible Products.
Research shows that delta-9-tetrahydrocannabinol (THC) is linked to increased anxiety, while cannabidiol (CBD) may have anxiolytic effects. Cannabis use is o…
The Endocannabinoid System in Obsessive-Compulsive Disorder: A Scoping Review.
About 40% of individuals suffering from obsessive-compulsive disorder (OCD) do not respond to current interventions such as pharmacotherapy and psychotherapy…
The role of cannabis-based medicinal products (CBMPs) in managing osteoarthritis symptoms: a scoping review of current evidence and future directions.
This review critically evaluates the therapeutic role of cannabis and its derivatives in managing osteoarthritic pain, with a focus on clinical evidence and …
Taurine attenuates lipid accumulation via the eCB-CB1 axis: evidence from adipose metabolomics in HFD-fed mice and 3D adipocyte spheroids.
Obesity, driven by adipose tissue dysfunction, is a major global health challenge and a key contributor to metabolic disorders. Although taurine shows anti-o…
Cannabinoids and cognition in Parkinson’s disease: Insights from animal models and emerging clinical evidence.
Parkinson’s disease (PD) is a progressive, multisystem neurodegenerative disorder characterized not only by motor impairments but also by a broad spectrum of…
Enhancing the endocannabinoid system to treat residual disease in relapse-free multiple sclerosis.
The recent introduction of High-Efficacy Therapies (HETs) in clinical practice has drastically reduced the frequency of acute inflammatory episodes and relap…