Cannabis Oil for Chronic Pain Chronic pain—a relentless companion for millions worldwide—has a knack for dodging the best efforts of conventional treatment regimes, leaving countless individuals in a perpetual state of discomfort...
Endorsements announced for the Doctor-Approved Cannabis Handbook
I'm absolutely thrilled to share with you the upcoming launch of my very own "Doctor-Approved Cannabis Handbook". This has been a labour of love, the fruit of years of intense research, and...
The Dose Dependence of Delta-9 THC in Place Conditioning Paradigms
Cannabis aversion in mice increases at higher doses of THC How much is too much when it comes to marijuana use? While marijuana in small doses can be rewarding, high doses could...
Cannabidiol as a New Treatment for Rare Forms of Epilepsy
New research shows that cannabidiol (CBD) can treat therapy refractory epileptic encephalopathies. Epilepsy is a chronic neurologic disorder characterized by a predisposition to seizures, with a prevalence of 8.5 per 1,000 people...
Tapping into the endocannabinoid system to ameliorate acute inflammatory flares and associated pain in mouse knee joints
The cannabinoid system of the human body is composed of lipid molecules called endocannabinoids, cannabinoid receptors they bind to - namely CB1 and CB2, and enzymes - molecular machineries that synthesize and...
Recent meta-analysis demonstrates that CBD has antioxidative and anti-inflammatory properties
A meta-analysis published in 2020 demonstrates that cannabidiol (CBD) may be beneficial for a number of diseases due to its effect on oxidative stress. More specifically, G-protein coupled receptors, along with their...
Cannabinomics: A novel approach to differentiating cannabis varieties
A recent study surveyed twenty varieties of cannabis using a novel technique that they refer to as cannabinomics. This technique employs mass spectrometry of the entire metabolome along with statistical analysis as...
Distinct Effects of 9-Tetrahydrocannabinol and Cannabidiol on Neural Activation During Emotional Processing
The plant Cannabis contains multiple compounds that likely possess distinct psychoactive properties. In fact, 9-Tetrahydrocannabinol (THC) and CBD, the two major constituents, were recently demonstrated to influence anxiety response – at neural,...
Daily-level associations between PTSD and cannabis use among young sexual minority women
Sexual minority women (SMW, i.e. lesbian, bisexual, and other women who partner with women) experience trauma exposure and posttraumatic stress disorder (PTSD) more frequently than heterosexual women. They are also more prone...
Associations of PTSD, chronic pain, and their comorbidity on cannabis use disorder: Results from an American nationally representative study
Post-traumatic stress disorder (PTSD) and chronic pain are two distinct conditions found to occur together in a large number of patients. In fact, symptoms of PTSD and chronic pain tend to worsen...