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Pain Improved, Cravings Did Not: A Buprenorphine Study
Medical cannabis with buprenorphine was associated with modest improvements in pain, sleep, and quality of life over three months in adults with opioid use disorder and chronic pain. Opioid-positive urine screens declined numerically, but the change was…
FDA Grants Cannabis Extract VER-01 Breakthrough Therapy Status for Pain
The FDA has awarded Breakthrough Therapy Designation to VER-01, a pharmaceutical-grade cannabis extract for chronic low back pain. This marks the first FDA breakthrough therapy cannabis designation for pain treatment, backed by Phase 3 trials showing…
Cannabinoid formulation patent describes improved controlled-release profile #6
A patent filing describes a controlled-release cannabinoid composition with potential therapeutic applications.
Therapeutic potential and pharmacological mechanisms of cannabinoids in alleviating chemotherapy-induced organ toxicity and adverse effects.
A comprehensive review examines how cannabinoids chemotherapy organ protection mechanisms could address treatment-limiting toxicities. While theoretical evidence suggests promise through anti-inflammatory and antioxidant pathways, clinical validation…
Cannabis Rescheduling Is Not the Story People Think It Is
The cannabis rescheduling clinical impact is being widely misunderstood. While federal policy shifts from Schedule I to Schedule III signal progress, they do not define how cannabis should be used in medical care. This analysis clarifies what changes,…
Cannabis Brain Health and Aging Brain: Beyond the Headlines
Public discussions regarding cannabis brain health and aging often fail to distinguish between recreational adolescent use and late-life therapeutic guidance. This clinical review breaks down recent data to show why the exposure definition and habit…
How Cannabis Interacts With the Aging Brain and Its Endocannabinoid System
Cannabis aging brain endocannabinoid system research shows that baseline endocannabinoid tone declines with age. This study demonstrates that cannabis produces larger proportional increases in key compounds like anandamide in older adults. These findings…
A Physician’s Interpretation of a 2,500-Study Review
Medical cannabis evidence remains more limited than many patients expect. A large JAMA review of over 2,500 studies highlights where clinical support exists and where it does not. This analysis clarifies what current medical cannabis evidence can…
Zurich’s Cannabis Trial Extension Highlights Swiss Access Models
Switzerland cannabis access models are evolving with Zurich's cannabis trial extension. This trial demonstrates promising safety and efficacy outcomes. The extension highlights important clinical implications for medical cannabis programs.
Cannabinoid-based Interventions for Behavioral Outcomes in Children and Adolescents with Autism Spectrum Disorder
Cannabinoid interventions autism spectrum disorder show promise for improving behavioral outcomes in children and adolescents. This systematic review highlights safety and effectiveness data. Families and clinicians should consider these findings…