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Distinct Effects of 9-Tetrahydrocannabinol and Cannabidiol on Neural Activation During Emotional Processing
This study explores the distinct effects tetrahydrocannabinol cannabidiol have on neural activation during emotional processing. Findings reveal CBD reduces limbic activation and anxiety, while THC increases anxiety and frontal brain activity. These…
Daily-Level Associations Between PTSD and Cannabis Use Among Young Sexual Minority Women
Sexual minority women experience higher rates of PTSD and cannabis use than heterosexual women. This study examines cannabis use and anxiety in this population. Understanding these daily-level associations is crucial for targeted interventions.
Associations of PTSD, Chronic Pain, and Cannabis Use Disorder
PTSD chronic pain cannabis use disorder is a complex condition affecting many patients. This study highlights how PTSD and chronic pain together increase the risk of cannabis use disorder. Understanding these associations helps guide safer medical…
Efficacy, Tolerability, and Safety of Cannabinoid Treatments in Rheumatic Diseases
The focus on cannabinoid treatments rheumatic diseases highlights their potential in managing pain and inflammation. This systematic review examines efficacy, tolerability, and safety data from randomized controlled trials. Findings suggest cautious…
The Role of Cannabinoids in Dermatology
Cannabinoids in dermatology have shown promising therapeutic effects for treating itch-related skin conditions. Medical cannabis creams reduce itching and improve skin dryness safely. Research continues on cannabinoids for broader dermatologic…
Cannabidiol Acts at 5-HT1A Receptors in the Human Brain: Relevance for Treating Temporal Lobe Epilepsy
Cannabidiol inverse agonist 5-HT1A receptor activity plays a key role in modulating neuronal excitability. This mechanism may contribute to cannabidiol's potential in epilepsy treatment. Understanding this interaction helps clarify cannabidiol's…
Safety and Tolerability of Cannabidiol in Parkinson Disease: An Open Label, Dose-Escalation Study
Parkinson disease patients often seek alternative treatments like cannabidiol. This study investigates the safety and tolerability of cannabidiol in Parkinson disease. Results show mild adverse events and potential symptom improvement.
Acute Effects of Partial CB1 Receptor Agonists on Cognition – A Meta-Analysis of Human Studies
This meta-analysis examines the acute effects of partial CB1 receptor agonists on cognition in healthy adults. The study highlights cognitive impairments including verbal learning and memory. Understanding these effects is crucial for medical and…
Cannabis Improves Obsessive-Compulsive Disorder—Case Report and Review of the Literature
Obsessive-compulsive disorder (OCD) severely impairs quality of life and involves intrusive obsessions and compulsions. Cannabis-based medicine OCD treatment shows promise in improving symptoms. Case reports highlight the potential benefits of…
Topical Cannabis-Based Medicines – A Novel, Effective Treatment for Non-Uremic Calciphylaxis Leg Ulcers
Topical cannabis medicines non-uremic calciphylaxis offer a novel approach for treating leg ulcers. This treatment interacts with the endocannabinoid system to promote wound closure and pain relief. Early clinical observations show promising results with…