To examine daily within-person associations between symptoms reported by people with multiple sclerosis (MS) and psychoactive substance use using ecological …
Cannabis Products and Contaminant Detection: Critical Review of Regulatory Oversight and Analytical Methodologies.
Cannabis legalization and consumption in the United States have accelerated over the past decade, resulting in a rapidly diversifying marketplace of medical …
Effect of cannabinol, tetrahydrocannabivarin and cannabidiol on voluntary alcohol consumption.
Previous studies have demonstrated that the endocannabinoid system plays a significant role in the development of alcohol use disorder (AUD), and CB1 recepto…
The effects of chronic cannabidiol administration on brain pathology and behavioral deficits found in the tau P301s-line PS19 mouse model of Alzheimer’s disease.
BackgroundCompounds derived from the plant
A comparison of collision factors and toxicologic characteristics for rural and urban drivers presenting to the emergency department after a vehicular collision.
Impaired driving is a significant public health and safety issue. There is limited information about the differences in toxicologic characteristics and colli…
The role of cannabinoid ligands in neurodegenerative diseases: emerging anti-inflammatory, immunomodulation and disease-modifying perspectives.
Neurodegenerative diseases (NDs) constitute a growing global health burden driven by population aging and remain without disease-modifying therapies. Althoug…
Analytical Challenges and Emerging Detection Strategies of Synthetic Cannabinoids in Horse Doping Control.
Synthetic cannabinoids (SCs) were originally synthesized to advance the understanding of the endocannabinoid system, facilitate disease research, and support…
Aryl-Cyclohexanone as a Potential CB2 Agonist: In Vitro and In Silico Evidence in Inflammatory Modulation.
Inflammation is an evolutionarily conserved adaptive process essential for host defense against harmful stimuli, aimed at restoring homeostasis. However, exa…
Cannabidiol as a Modulator of the Gut-Liver Axis: Clinical and Pharmacological Insights into Hepatic and Metabolic Disorder Therapies.
A non-intoxicating substance produced from Cannabis sativa, cannabidiol (CBD) has shown promise as a treatment for metabolic and hepatic diseases, primarily …
Assessments of Evoked and Spontaneous Pain Following Administration of Gabapentin and the Cannabinoid CB
Cannabinoid CB We compared the impact of LY2828360 on evoked and spontaneous pain in a spared nerve injury (SNI) model using a within-subjects design in rats…