Sensitivity of the Fasciae to the Endocannabinoid System: Production of Hyaluronan-Rich Vesicles and Potential Peripheral Effects of Cannabinoids in Fascial Tissue In Summary Myofascial tissue is a thin, strong, fibrous connective tissue...
The endocannabinoid receptor CB2 is a regulator of trauma-inducing anxiety and a potential target for PTSD drugs
Cannabinoid CB2 receptors mediate the anxiolytic-like effects of monoacylglycerol lipase inhibition in a rat model of predator-induced fear In Summary Researchers recently identified a signaling pathway in the endocannabinoid system that regulates...
The wide distribution of cannabinoid receptors in the gastrointestinal tract suggests cannabinoids like CBD can relieve GI pain
Localization of cannabinoid and cannabinoid related receptors in the cat gastrointestinal tract In Summary Cannabidiol (CBD) is a component of the plant cannabis with great potential for medical applications because of its...
Activation of the cannabinoid receptor type 2 reduce damages to the brain and disruptions to the spinal cord during ischemia-reperfusion injury
Exogenous activation of cannabinoid-2 receptor modulates TLR4/MMP9 expression in a spinal cord ischemia reperfusion rat model In Summary Ischemia is the restriction in blood supply, causing a shortage of oxygen and resulting...
Cannabis Use in Patients With Heart Disease
Marijuana use is associated with heightened risks for many heart diseases while interfering with therapies In Summary Cannabis use is increasing throughout the US as more states legalize marijuana for both medicinal...
An unknown cannabinoid receptor helps alleviate secondary brain damages through regulating microglial cells and astrocytes of the brain.
Abnormal Cannabidiol Affects Production of Pro‐Inflammatory Mediators and Astrocyte Wound Closure in Primary Astrocytic‐Microglial Cocultures In Summary Damage to the brain such as brain trauma or stroke comprises two consecutive events. The...
Neurological and neurodegenerative conditions, physical activities, and the endocannabinoid system – how might all these be linked?
Can physical activity support the endocannabinoid system in the preventive and therapeutic approach to neurological disorders? In Summary The endocannabinoid signaling system (ECS) of the body includes naturally produced chemicals called cannabinoids,...
Urgent need for clinical trials investigating the effects of cannabinoids on hormone receptor-positive breast cancer therapy
Cannabinoids and Hormone Receptor-Positive Breast Cancer Treatment In Summary Breast cancer (BC) is the most common cancer in women worldwide. Approximately 70-80% of BC cases fall into the category of hormone...
Benefits of cannabidiol on skin cells are compromised in psoriasis patients receiving UV irradiation treatment
Cannabidiol Effects on Phospholipid Metabolism in Keratinocytes from Patients with Psoriasis Vulgaris In Summary Endocannabinoid is a group of lipids naturally produced by the body. The endocannabinoid system, which includes mainly endocannabinoids...
Cannabinoid receptor type 2 as a promising new target for schizophrenia drugs
Contribution of CB2 receptors in schizophrenia-related symptoms in various animal models In Summary Schizophrenia is a serious, chronic mental disorder that disrupts how a person thinks, feels and behaves. Its psychotic (also...