For years, cannabis has been a controversial plant, fueling debates in many sectors, from botanical taxonomy to applied therapeutics to politics. In the sphere of taxonomy, debates regarding the speciation of Cannabis,...
The Effects of Cannabis sativa L. Seed (Hemp Seed) on Reproductive and Neurobehavioral End Points in Rats
Hemp is defined as a cannabis plant with 0.3% or less THC - the compound responsible for the psychoactive effects of marijuana - in constituents. Marijuana, and specifically THC, were found by...
A Survey on the Effect That Medical Cannabis Has on Prescription Opioid Medication Usage for the Treatment of Chronic Pain at Three Medical Cannabis Products
The US opioid epidemic has continued unabated, accounting for 47,600 overdose deaths in 2017, highlighting the urgent need for substitutes with similar pain-relieving effects but without addictive properties. The use of cannabis...
Role of cannabis components on the regenerative ability of stem cells
Previous research has extensively demonstrated the abilities of cannabidiol (CBD) and tetrahydrocannabinol (THC), two main cannabinoids derived from the plant cannabis, to regulate the proliferation, migration, and differentiation of stem cells. For...
Acute Effect of Electronic Cigarette-Generated Aerosol From Flavored CBD-Containing Refill Solutions on Human Bronchial Epithelial Cells
Currently, most commercially available CBD-containing e-cigarettes and refill solutions come in a wide array of flavors, the chemical constituents of which are often not fully disclosed by manufacturers. Emerging evidence that these...
An Analysis of Over-the-Counter Cannabidiol Products in the United Kingdom
Cannabidiol (CBD), one of the major constituents of the plant cannabis, has received increasing interest in the United Kingdom in recent years for valid reasons. Research has proven its broad range of...
Cannabidiol Acts at 5-HT1A Receptors in the Human Brain: Relevance for Treating Temporal Lobe Epilepsy
Epilepsy is a very common disorder characterized by recurrent, spontaneous seizures, and a seizure is induced by the abnormal, synchronous excitation of neurons in the brain. Gi/o proteins inside neurons, when activated,...
Use of Dronabinol Improves Appetite and Reverses Weight Loss in HIV/AIDS-Infected Patients
HIV wasting syndrome is defined as the involuntary loss of more than 10% of baseline body weight and is associated with chronic diarrhea, weakness, or fever. This common complication of HIV has...
No Acute Effects of Cannabidiol on the Sleep-Wake Cycle of Healthy Subjects: A Randomized, Double-Blind, Placebo-Controlled, Crossover Study
Cannabidiol (CBD) is a component of the plant cannabis with various therapeutic benefits including antidepressant and anxiolytic (anxiety-relieving). Despite being a known regulator of brain functions (hence its benefits against the above...
Substitution of medical cannabis for pharmaceutical agents for pain, anxiety, and sleep
Until now, medical cannabis remains a highly controversial substance, being condoned in different forms by half of the states but prohibited at a federal level in the states. A plethora of scientific,...