Association of Multimodal Cannabis Use with Adverse Events among Adolescents and Young Adults.

Association of Multimodal Cannabis Use with Adverse Events among Adolescents and Young Adults.

CED Clinical Relevance  #56Monitored Relevance  Early-stage or contextual signal requiring further evidence before action.
🔬 Evidence Watch  |  CED Clinic
Journal American journal of preventive medicine
Study Type Clinical Study
Population Human participants
Why This Matters

This item covers developments relevant to cannabis medicine and clinical practice. Clinicians monitoring evidence in this area should review the source material.

Clinical Summary

The ways cannabis is consumed, or modes of use, have increased and diversified in recent years, especially among young people. Associations of multimodal cannabis use (1, 2, or 3+ modes) with adverse events were examined among adolescents and young adults. Data from the 2022-2023 National Survey of Drug Use and Health, including non-institutionalized US civilians aged 12-25 reporting past-year cannabis use (n=13,284), were used. Cannabis users were asked about the type (smoking, vaping, dabbing, eating/drinking, and other) and number of cannabis modes used in the past year. Multivariable-adjusted analyses assessed associations of number of modes with adverse events, adjusted for sociodemographic characteristics and frequency of use. Among 51,435 individuals (45.8% adolescents, 51.0% female, 48.1% non-Hispanic white), 13,284 (26.1%) reported past-year cannabis use. Individuals more frequently used 3+ modes (37.5%) than one (34.0%) or two (28.5%), with the most common being smoking (83.9

Dr. Caplan’s Take

“This is a development worth tracking. The clinical implications will become clearer as more evidence accumulates.”

Clinical Perspective
🧠 Clinicians should review this item in the context of their current practice and patient population.

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FAQ

This study item was assembled from normalized source metadata and pipeline scoring.







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