Clinical Takeaway Cannabinoids have been studied across a range of pediatric medical conditions, with the current evidence base drawing from over 270 studies including both interventional and observational designs. The available data...
`Cannabinoid Clinical Trials: Full-Spectrum Cannabis for Back Pain`
Clinical Takeaway In this phase 3 randomized controlled trial of 820 adults with chronic low back pain, the full-spectrum cannabis extract VER-01 was evaluated over a 12-week double-blind period with up to...
Endocannabinoid System: Cannabis for Chronic Pain Review
Clinical Takeaway Clinical trials show that cannabis-based products, particularly those containing THC, provide modest reductions in chronic pain compared to placebo, though the overall quality of evidence remains low to moderate. Benefits...
Cannabinoid Formulations for Anxiety and Tourette Syndrome
Clinical Takeaway Cannabinoid formulations, particularly CBD-containing products, show measurable reductions in anxiety symptoms across multiple study designs, though effect sizes and optimal dosing remain inconsistent across trials. Evidence for Tourette syndrome is...
Endocannabinoid System Research: Cannabis for Endometriosis
Clinical Takeaway Researchers attempted a three-armed randomized controlled trial comparing inhaled THC-dominant cannabis, an oral cannabis oil, and placebo for endometriosis pain, but encountered significant feasibility challenges that limited their ability to...
Topical Cannabis for AIMSS: Cannabinoid Clinical Trials
Clinical Takeaway Topical cannabis balms were tested in a randomized trial for postmenopausal breast cancer patients experiencing joint pain and stiffness caused by aromatase inhibitor therapy. The study evaluated whether this approach...
Endocannabinoid System Research: Cannabis & Autism Review
Clinical Takeaway Cannabinoid-based treatments, including CBD-rich preparations, have shown preliminary benefits for certain autism-related symptoms such as irritability, hyperactivity, and sleep difficulties in clinical trial data. The evidence base remains limited in...
Endocannabinoid System Research: CBD & Cortical Excitability
Clinical Takeaway In a controlled crossover trial in healthy adults, CBD at both low and high doses showed no direct effect on cortical excitability compared to placebo, suggesting its anti-seizure benefit may...
endocannabinoid system clinical research: Mobile Mental Health
Clinical Takeaway A randomized controlled trial tested the Minder mobile app, co-developed with university students, to address mental health and substance use challenges during the college transition period. Digital tools like this...
`Endocannabinoid System & Cannabis for Chronic Back Pain Trial`
Clinical Takeaway In this phase 3 trial of 820 adults with chronic low back pain, the full-spectrum cannabis extract VER-01 was evaluated against placebo over 12 weeks with extended follow-up periods reaching...