CBM treatments may improve pain scores, but study limitations such as small sample sizes and study durations, high placebo response rates, and trial unblinding because of the psychoactive effects of cannabinoids all hinder data interpretation and the extrapolation to chronic pain conditions.
Cannabis Medicines Show Modest Promise for Nerve Pain, But Evidence Remains Inconclusive
CBM treatments may improve pain scores, but study limitations such as small sample sizes and study durations, high placebo response rates, and trial unblinding because of the psychoactive effects of cannabinoids all hinder data interpretation and the extrapolation to chronic pain conditions.
CBD in Childhood Epilepsy: What the Evidence Actually Shows
Several randomized controlled trials in children and adults with epilepsy syndromes such as Lennox-Gastaut syndrome and Dravet syndrome have demonstrated meaningful reduction in seizures following the administration of cannabidiol.
Cannabis for Nerve Pain: Mixed Evidence From 22 Trials, No Clear Winners Yet
Collectively, CBM treatments may improve pain scores, but study limitations such as small sample sizes and study durations, high placebo response rates, and trial unblinding because of the psychoactive effects of cannabinoids all hinder data interpretation and the extrapolation to chronic pain conditions.
What the Evidence Really Says About CBD for Children With Epilepsy
Several randomized controlled trials in children and adults with epilepsy syndromes such as Lennox-Gastaut syndrome and Dravet syndrome have demonstrated meaningful reduction in seizures following the administration of cannabidiol.
CBD for Childhood Epilepsy: What the Evidence Actually Shows
In a multicenter open label prospective interventional trial in patients aged 1–30 years with DRE, oral CBD titrated up to 25 mg/kg/day showed 36.5% median percentage reduction in monthly motor seizures after 12 weeks; more than 50% reduction in seizures was noted in 39% of patients.
CBD in Vaporised Cannabis Boosts THC Levels in the Blood, Study Finds
The ‘THC+CBD’ condition produced significantly greater THC, OH-THC, and COOH-THC plasma levels than the ‘THC-alone’ condition, in terms of natural-log-transformed area-under-the-curve (AUC) and peak concentration (Cmax) values, with the exception of Cmax for OH-THC.
CBD in Vaporised Cannabis Raises THC Blood Levels, Study Finds—but Age Differences Remain Unclear
The ‘THC+CBD’ condition produced significantly greater THC, OH-THC, and COOH-THC plasma levels than the ‘THC-alone’ condition, in terms of natural-log-transformed area-under-the-curve (AUC) and peak concentration (Cmax) values, with the exception of Cmax for OH-THC.
Evidence-based therapist guided introduction to online heavy cannabis use treatment in Canadian adults: a Randomized Controlled Trial (RCT).
Many people who engage in heavy cannabis use do not seek treatment, and those who do are often met with long treatment wait times or high cost of services. O…
Cannabidiol in Anorexia Nervosa: A Double-Blind Randomized Placebo Controlled Pilot Study to Test Safety, Pharmacokinetics, and Symptom Change.
Anorexia nervosa (AN) is a severe psychiatric disorder marked by an intense fear of gaining weight and persistent body dissatisfaction, both during periods o…