Clinical Takeaway Clinical trials show that cannabis-based products, particularly those containing THC, provide modest but measurable reductions in chronic pain compared to placebo. The evidence is categorized by THC-to-CBD ratio, source, and...
Endocannabinoid System Research: Cannabis for Endometriosis
Clinical Takeaway Medicinal cannabis is widely self-reported by people with endometriosis for pain relief, but rigorous clinical trial data confirming its efficacy remain absent. This Australian feasibility trial tested inhaled THC-dominant cannabis...
Endocannabinoid System Research: Cannabis for Autism
Clinical Takeaway Across randomized clinical trials, cannabis derivatives and their analogs showed promising early signals for improving core and associated symptoms of autism spectrum disorder, including social communication and behavioral challenges. The...
`Cannabinoid Clinical Trials: CBD Cortical Excitability Study`
Clinical Takeaway In a controlled crossover trial of healthy males, neither a low (30 mg) nor a high (700 mg) single dose of CBD produced measurable changes in cortical excitability compared to...
Cannabinoid Clinical Trials: Sleep, EEG & Insomnia RCT
Clinical Takeaway In this small pilot trial of 20 adults with diagnosed insomnia disorder, a single oral dose of 10 mg THC combined with 200 mg CBD reduced total sleep time compared...
endocannabinoid system clinical research: mobile mental health
Clinical Takeaway A randomized controlled trial tested the Minder mobile app, co-developed with university students, to address mental health and substance use during the high-risk college transition period. Digital tools like this...
Cannabinoids for Pediatric Care: Evidence-Based Clinical Review
Clinical Takeaway Pediatric cannabinoid research is an active and growing field, with 276 studies identified across multiple designs, reflecting real-world clinical use across a range of medical conditions in children under 18....
`Cannabinoid Clinical Trials: Cannabis for Chronic Back Pain`
Clinical Takeaway In this phase 3 randomized controlled trial of 820 adults, the full-spectrum cannabis extract VER-01 was evaluated against placebo over 12 weeks for chronic low back pain, with follow-up extending...
Endocannabinoid System Research: Cannabis for Chronic Pain
Clinical Takeaway Randomized controlled trial evidence through mid-2025 shows that cannabinoids provide modest pain relief for some chronic pain conditions, with effects varying based on THC-to-CBD ratio, product source, and route of...
endocannabinoid system clinical research: Mobile Mental Health RCT
Clinical Takeaway A mobile app called Minder, co-designed with university students, was tested in a randomized controlled trial to address mental health and substance use challenges that commonly emerge during the college...