Previously, nabilone showed a medium effect size for treating agitation in moderate-to-severe Alzheimer’s disease (AD), but response varied. These post hoc a…
Investigating the effects of cannabinoids for the reduction of inflammation and sickle cell disease pain (CRISP); A protocol for a randomized double-blind placebo-controlled study.
Sickle Cell Disease (SCD) is a hemoglobinopathy affecting millions of people globally. Pain, both acute and chronic, affects over half of those living with S…
Cannabidiol blood metabolite levels after cannabidiol treatment are associated with broadband EEG changes and improvements in visuomotor and non-verbal cognitive abilities in boys with autism requiring higher levels of support.
Oral cannabidiol (CBD) treatment has been suggested to alleviate severe symptoms of autism spectrum disorder (ASD). While many CBD preparations have been stu…
Effects of Cannabidiol on Social Relating, Anxiety, and Parental Stress in Autistic Children: A Randomized Controlled Crossover Trial.
Cannabidiol (CBD), a non-intoxicating compound derived from the cannabis plant, has garnered increasing attention as a potential pharmacological therapeutic …
Effects and safety of a CBD-rich
Osteoarthritis is a common inflammatory and degenerative joint disease characterized by associated chronic pain, often ensuing to diminished quality of life….
Cannabis effects on cardiovascular health: Current evidence, gaps in knowledge, and future research directions.
As cannabis use accelerates globally with expanding legalization and availability of high-potency formulations, concerns regarding its cardiovascular safety …
Investigational drugs in PTSD.
Post-traumatic stress disorder (PTSD) remains one of psychiatry’s most challenging disorders, common, disabling, and biologically complex. Despite decades of…
Randomised Controlled Trial Evidence on Medicinal Cannabis for Treatment of Mental Health and Substance Use Disorders: A Scoping Review.
With shifting perceptions about the therapeutic potential of cannabis and evolving regulatory frameworks, global prescribing of medicinal cannabis is increas…
The effect of daily aerobic cycling exercise on cannabis withdrawal: An inpatient randomised controlled trial.
Aerobic exercise can reduce withdrawal symptoms from tobacco and other drugs but its potential to alleviate cannabis withdrawal remains unexplored. This stud…
Effect of Cannabigerol on Sleep and Quality of Life in Veterans: A Decentralized, Randomized, Placebo-Controlled Trial.
This decentralized, randomized, triple-blind, placebo-controlled study evaluated efficacy and safety of oral cannabigerol (CBG) in Veterans with sleep issues…