Anandamide (AEA), an endogenous cannabinoid, is thought to exert an inhibitory role in the basolateral amygdala complex (BLA), dampening hypothalamus-pituita…
Hemp seed extract exerts cytostatic effects through metabolic stress and autophagy modulation in malignant cells.
Phytocannabinoids from Cannabis sativa L. exhibit anticancer activity, but how the polar fraction from cold-pressed hemp seed oil derived from industrial cul…
Potential effects of cannabidiol on formalin-induced inflammatory pain in morphine-dependent rats.
Chronic morphine exposure leads to tolerance and dependence, complicating pain management and reducing the efficacy of opioid analgesics. Cannabidiol (CBD), …
A sesquiterpene-rich essential oil from Cannabis sativa L. attenuates symptoms and neuroinflammation in experimental autoimmune encephalomyelitis model through a CB2-mediated signalling.
The efficacy of cannabinoid-based medication as analgesic and neuroprotective in multiple sclerosis (MS) has been described, but little is known on other can…
Exploring the neuroprotective effects of phytocannabinoids on oxygen-glucose deprived neurons in an in vitro model of stroke.
Stroke is a leading cause of death and disability worldwide, but therapeutic options to reduce or prevent neuronal damage are extremely limited. Cannabinoids…
Prenatal cannabis smoke exposure alters placental development in a murine model of pregnancy.
Cannabis use during pregnancy continues to increase with smoking remaining the most common mode of consumption. While clinical studies highlight an associati…
CBD And CBG From The Cannabis Plant Could Help Treat A Common Liver Condition | IFLScience
✦ New CED Clinical Relevance #70Notable Clinical Interest Emerging findings or policy developments worth monitoring closely. ⚒ Cannabis News | CED Clinic Liver DiseaseCbdCbgPreclinical ResearchNafld Why This MattersNon-alcoholic fatty liver disease affects nearly 25% of US...
Inhaled CBD Reduces Key Neuroinflammatory Markers in Alzheimer’s Mouse Model
CBD treatment significantly reduced IDO and cGAS expression, correlating with decreased proinflammatory cytokines, including TNF-ฮฑ, IL-1ฮฒ, and IFN-ฮณ. These findings support CBD as a potential monotherapy or adjunctive treatment for AD by targeting distinct neuroinflammatory pathways.
Cannabis Compound Shows Promise in Fighting Alzheimer’s by Calming Brain Inflammation
✦ New CED Clinical Relevance #70Notable Clinical Interest Emerging findings or policy developments worth monitoring closely. ⚒ Cannabis News | CED Clinic Alzheimer'SNeuroinflammationNeuroprotectionPreclinical ResearchDementia Why This MattersAlzheimer's disease affects over 6 million Americans with limited therapeutic...