Clinical Takeaway Trauma-focused therapy remains effective for PTSD even in patients who are actively using cannabis, including those with co-occurring substance use disorders. Patients should not be required to stop cannabis use...
Medical Cannabis for Anxiety & Tourette: Clinical Evidence
Clinical Takeaway Cannabinoid formulations, particularly those containing CBD alone or in combination with THC, show measurable reductions in anxiety symptoms across multiple anxiety-related disorders, including Tourette syndrome, based on pooled clinical trial...
`Cannabinoid Clinical Trials: CBD vs Placebo in Fibromyalgia`
Clinical Takeaway In this randomized, double-blind, placebo-controlled trial, CBD did not demonstrate superiority over placebo in reducing pain among patients with fibromyalgia. The findings do not support the use of CBD as...
Endocannabinoid System Research: Cannabinoids for Children
Clinical Takeaway Cannabinoids have been studied across a range of pediatric medical conditions, with the current evidence base drawing from hundreds of studies including clinical trials and observational reports. The strongest and...
Cannabinoids in Pediatric Care: Evidence-Based Clinical Review
Clinical Takeaway Most of the current evidence on cannabinoid use in children comes from observational studies and surveys rather than controlled trials, reflecting the early and evolving state of this research. The...
Cannabinoid Clinical Trials in Athlete Mental Health Care
Clinical Takeaway Retired professional athletes from high contact team sports show elevated rates of depression, anxiety, and cognitive concerns compared to the general population, with career-related head trauma and abrupt identity loss...
Cannabidiol for Lennox-Gastaut: Cannabinoid Clinical Trials
Clinical Takeaway Plant-derived cannabidiol (CBD) oral solution produced meaningful reductions in drop seizures in patients with Lennox-Gastaut syndrome at thresholds below the traditional 50% benchmark used in clinical trials. Caregiver-reported outcomes aligned...
Endocannabinoid System Research: Cannabis for Chronic Pain
Clinical Takeaway Clinical trials show that cannabis-based products, particularly those with higher THC content, provide modest reductions in chronic pain compared to placebo, though the overall strength of evidence remains low to...
Endocannabinoid System Research: Cannabis for Chronic Pain
Clinical Takeaway Clinical trials show that cannabis-based products containing THC provide modest reductions in chronic pain compared to placebo, though the overall strength of evidence remains low to moderate. Products vary considerably...
Cannabidiol as a Therapeutic Alternative for Post-traumatic Stress Disorder: From Bench Research to Confirmation in Human Trials
Post-traumatic stress disorder (PTSD) is characterized by difficulties that a person faces when recovering from experiencing or witnessing a terrifying event. It affects approximately 10% of the population at some point in...