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PP-01 for Cannabis Withdrawal: What a 14-Person Trial Found
PP-01 for cannabis withdrawal was associated with improved symptom ratings, sleep, and craving in a randomized 14-person crossover trial. The study lasted five nights in an inpatient setting and reported mild adverse events with no serious adverse…
How the Body Switches Off Its Own Cannabinoids, and What Happened When a Drug Company Tried to Stop It
Endocannabinoid degradation runs through two enzymes: FAAH, which converts anandamide to arachidonic acid and ethanolamine, and MAGL, which converts 2-AG to arachidonic acid and glycerol and handles about 85 percent of brain 2-AG hydrolysis. Blocking…
Target trial emulations for tirzepatide, semaglutide and SGLT2-inhibitors for dementia
A recent study indicates that tirzepatide may reduce incident dementia more than semaglutide or SGLT2 inhibitors in adults with type 2 diabetes.
Pain Suzetrigine Data Reveal Reduced Postoperative Opioids
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Reclassification of marijuana opens doors for much-needed medical research into the … – Seattle PI
The potential reclassification of cannabis from Schedule I to Schedule III could significantly reduce medical research barriers that have limited clinical evidence generation for decades. This regulatory shift would maintain federal oversight while…
Financial news in brief: Avecho CBD trial latest; Argent’s milestone delivery – Cannabiz
Pharmaceutical CBD clinical trial development represents important progress in cannabis therapeutics, though patients should maintain realistic expectations about timing and superiority over current protocols. Understanding the distinction between…
UWIFIC and Antigua and Barbuda Medicinal Cannabis Authority Formalise Research and …
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Federal Marijuana reclassification could reshape medical research and cannabis industry
Federal marijuana rescheduling medical research represents a pivotal moment for cannabis medicine, potentially removing decades-old barriers to rigorous clinical studies. This policy shift could accelerate the development of evidence-based cannabis…
Federal Marijuana reclassification could reshape medical research and cannabis industry
Federal marijuana reclassification medical research changes could remove decades-old barriers to clinical trials and evidence generation. This regulatory shift may fundamentally transform how clinicians approach cannabis medicine with proper scientific…
Cannabis Use, Cognition, and the Endocannabinoid System in HIV
A new observational study investigating cannabis cognitive effects in HIV patients addresses critical knowledge gaps in medical marijuana guidance. This research could establish therapeutic windows and safety profiles for cannabis use in HIV populations.…