This narrative review examines whether the endocannabinoid system may play a biochemical role in ADHD pathophysiology. It gathers 11 preclinical and 2 clinical studies and argues that ECS signaling may intersect with attention, impulsivity, and hyperactivity pathways. The core limitation is that the evidence remains thin, heavily preclinical, and far from proving that cannabinoid-based treatments are ready for clinical use in ADHD.
A sesquiterpene-rich essential oil from Cannabis sativa L. attenuates symptoms and neuroinflammation in experimental autoimmune encephalomyelitis model through a CB2-mediated signalling.
The efficacy of cannabinoid-based medication as analgesic and neuroprotective in multiple sclerosis (MS) has been described, but little is known on other can…
CB2R-mediated GPX4 stabilization: a new avenue for treating cognitive impairment in elderly migraine patients.
Migraine is frequently associated with cognitive impairment, a pathology linked to microglial dysfunction and neuroinflammation. Ferroptosis, a form of iron-…
5 Alarming Truths About Cannabis and Heart Health
In the age of legalization, cannabis is stepping into the spotlightโbut its cardiovascular effects are still under-discussed. While some compounds like CBD show promise, others, like THC and synthetic cannabinoids, pose serious risks to heart health. This blog peels back the layers of science and sentiment to deliver an honest look at how cannabis interacts with the most vital organ in your body.
(โ)-ร-Caryophyllene, a Terpine Found in Cannabis, Demonstrates Therapeutic Potential in a Mouse Model of MS
(โ)-ฮฒ-Caryophyllene, a CB2 Receptor-Selective Phytocannabinoid, Suppresses Motor Paralysis and Neuroinflammation in a Murine Model of Multiple Sclerosis In Summary Multiple sclerosis (MS) is a central nervous system disease whose inflammatory and other...