Letter by Wu et al Regarding Article, “G Protein-Coupled Receptor Kinase 3 Exacerbates Diabetic Heart Injuries Through Direct Phosphorylation of Cannabinoid Receptor 2 in Humans and Mice”.
Laboratory research published in Circulation identifies how diabetes may worsen heart complications through disruption of cannabinoid receptor 2 function. This diabetic heart disease cannabinoid receptor research provides mechanistic insights but…
A sesquiterpene-rich essential oil from Cannabis sativa L. attenuates symptoms and neuroinflammation in experimental autoimmune encephalomyelitis model through a CB2-mediated signalling.
Researchers found that cannabis essential oil neuroinflammation reduction occurred through CB2 receptor activation in an experimental multiple sclerosis model. The sesquiterpene-rich formulation improved pain, motor function, and emotional symptoms…
Evaluating CB2 Receptor Agonist Effects on Neuropathic Pain
This study highlights cb2 receptor agonist neuropathic pain treatment as a promising approach to reduce both evoked and spontaneous pain. The preclinical findings suggest potential benefits for managing neuropathic pain. Further human studies are needed…
Research Digest: 30 Recent Studies (CB1, CB2 Receptors) – March 16, 2026
This research digest presents recent cannabis research studies focusing on CB1 and CB2 receptors. It summarizes 30 of the most recent clinical studies curated for relevance and evidence quality. These recent cannabis research studies provide valuable…
(—)-ß-Caryophyllene, a Terpine Found in Cannabis, Demonstrates Therapeutic Potential in a Mouse Model of MS
(—)-β-Caryophyllene, a CB2 Receptor-Selective Phytocannabinoid, Suppresses Motor Paralysis and Neuroinflammation in a Murine Model of Multiple Sclerosis In Summary Multiple sclerosis (MS) is a central nervous system disease whose inflammatory and other…