Letter by Wu et al Regarding Article, “G Protein-Coupled Receptor Kinase 3 Exacerbates Diabetic Heart Injuries Through Direct Phosphorylation of Cannabinoid Receptor 2 in Humans and Mice”.
Laboratory research published in Circulation identifies how diabetes may worsen heart complications through disruption of cannabinoid receptor 2 function. This diabetic heart disease cannabinoid receptor research provides mechanistic insights but…
A sesquiterpene-rich essential oil from Cannabis sativa L. attenuates symptoms and neuroinflammation in experimental autoimmune encephalomyelitis model through a CB2-mediated signalling.
Researchers found that cannabis essential oil neuroinflammation reduction occurred through CB2 receptor activation in an experimental multiple sclerosis model. The sesquiterpene-rich formulation improved pain, motor function, and emotional symptoms…
Assessments of Evoked and Spontaneous Pain Following Administration of Gabapentin and the Cannabinoid CB
A preclinical study demonstrates that CB2 receptor agonist neuropathic pain treatment may address both mechanical hypersensitivity and spontaneous pain components. While promising mechanistically, this research requires human validation before clinical…
Research Digest: 30 Recent Studies (CB1, CB2 Receptors)- March 16, 2026
CED Clinical Relevance #85 Research Authority Peer-reviewed research curated for clinical relevance and evidence quality. Recent research digest. 30 of 30 most recent studies from our monitored feeds. CED Clinical Relevance #81 Research Authority Towards…
(—)-ß-Caryophyllene, a Terpine Found in Cannabis, Demonstrates Therapeutic Potential in a Mouse Model of MS
(—)-β-Caryophyllene, a CB2 Receptor-Selective Phytocannabinoid, Suppresses Motor Paralysis and Neuroinflammation in a Murine Model of Multiple Sclerosis In Summary Multiple sclerosis (MS) is a central nervous system disease whose inflammatory and other…
