Fear of recurrence, secondary cancers, and health problems in long-term survivors of childhood cancer: Findings from a Canadian cohort.

CED Clinical Relevance  #60Notable Clinical Interest  Emerging findings or policy developments worth monitoring closely.
🔬 Evidence Watch  |  CED Clinic
Journal Cancer
Study Type Cohort
Population Human participants
Why This Matters

This item covers developments relevant to cannabis medicine and clinical practice. Clinicians monitoring evidence in this area should review the source material.

Clinical Summary

Survivors of childhood cancer are at lifelong risk for health problems, secondary cancers, and recurrence. However, little is known about their fears related to these risks nor the factors associated with them. A Canadian cohort of childhood cancer survivors (nย =ย 284; 51.1% male; mean ageย =ย 22.3 years, mean time off treatmentย =ย 12.4 years) reported on their fears of health problems, secondary cancers, and recurrence; physical functioning; psychosocial symptoms; and substance use. The relationship between their fears and various demographic, physical, and psychosocial variables was assessed through multivariate logistic regression analyses. Thirty-seven percent of survivors reported at least one cancer fear. Fear of secondary cancer was the most reported (25.0%), followed by fear of future health problems (24.6%) and fear of recurrence (21.8%). Survivors who reported having ever drunk to intoxication were more likely to report all three cancer fears (psย <ย .01-<.05) and those who endorse

Dr. Caplan’s Take

“This is a development worth tracking. The clinical implications will become clearer as more evidence accumulates.”

Clinical Perspective
🧠 Clinicians should review this item in the context of their current practice and patient population.

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