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endocannabinoid system clinical research: Mobile Mental Health

Clinical Takeaway

A randomized controlled trial tested the Minder mobile app, co-developed with university students, to address mental health and substance use concerns during a high-risk transitional period. The study evaluated whether this digital tool could produce measurable improvements in psychological wellbeing and substance use behaviors at a population level. Mobile interventions like Minder offer a scalable, accessible option for reaching students who may not seek traditional clinical care.

endocannabinoid system clinical research: Mobile Mental Health

#4 Effectiveness of the Minder Mobile Mental Health and Substance Use Intervention for University Students: Randomized Controlled Trial.

Citation: Vereschagin Melissa et al.. Effectiveness of the Minder Mobile Mental Health and Substance Use Intervention for University Students: Randomized Controlled Trial.. Journal of medical Internet research. 2024. PMID: 38536225.

Study type: Randomized Controlled Trial, Journal Article, Research Support, Non-U.S. Gov’t  |  Topic area: Anxiety & PTSD  |  CED Score: 12

Design: 5 Journal: 0 N: 3 Recency: 1 Pop: 2 Human: 1 Risk: 0

Abstract: BACKGROUND: University attendance represents a transition period for students that often coincides with the emergence of mental health and substance use challenges. Digital interventions have been identified as a promising means of supporting students due to their scalability, adaptability, and acceptability. Minder is a mental health and substance use mobile app that was codeveloped with university students. OBJECTIVE: This study aims to examine the effectiveness of the Minder mobile app in improving mental health and substance use outcomes in a general population of university students. METHODS: A 2-arm, parallel-assignment, single-blinded, 30-day randomized controlled trial was used to evaluate Minder using intention-to-treat analysis. In total, 1489 participants were recruited and randomly assigned to the intervention (n=743, 49.9%) or waitlist control (n=746, 50.1%) condition. The Minder app delivers evidence-based content through an automated chatbot and connects participants with services and university social groups. Participants are also assigned a trained peer coach to support them. The primary outcomes were measured through in-app self-assessments and included changes in general anxiety symptomology, depressive symptomology, and alcohol consumption risk measured using the 7-item General Anxiety Disorder scale, 9-item Patient Health Questionnaire, and US Alcohol Use Disorders Identification Test-Consumption Scale, respectively, from baseline to 30-day follow-up. Secondary outcomes included measures related to changes in the frequency of substance use (cannabis, alcohol, opioids, and nonmedical stimulants) and mental well-being. Generalized linear mixed-effects models were used to examine each outcome. RESULTS: In total, 79.3% (589/743) of participants in the intervention group and 83% (619/746) of participants in the control group completed the follow-up survey. The intervention group had significantly greater average reductions in anxiety symptoms measure

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