Cannabinoid Clinical Trials: Cannabis Intervention in Teens

Clinical Takeaway

Tailored cannabis prevention messaging that first addresses and refutes adolescents’ negative reactions to anti-cannabis appeals, then delivers a third targeted communication, shows promise as a more effective approach than one-size-fits-all campaigns. Standard prevention messages often fail because they do not account for the wide variation in how adolescents think and feel about cannabis use. Sequencing messages to match individual attitudes and social norms may improve engagement and receptivity among at-risk youth.

#26 A Rebuttal-Based Social Norms-Tailored Cannabis Intervention for At-Risk Adolescents.

Citation: Donaldson Candice D et al.. A Rebuttal-Based Social Norms-Tailored Cannabis Intervention for At-Risk Adolescents.. Prevention science : the official journal of the Society for Prevention Research. 2021. PMID: 33791930.

Study type: Journal Article, Randomized Controlled Trial, Research Support, N.I.H., Extramural  |  Topic area: Pediatrics  |  CED Score: 10

Design: 5 Journal: 0 N: 3 Recency: 0 Pop: 3 Human: 1 Risk: -2

Quality Gate Alerts:

  • Preclinical only

Abstract: Many past cannabis prevention campaigns have proven largely ineffective due in part to the diversity of adolescents’ cannabis-relevant beliefs. The current studies evaluated the impact of a sequential multiple message approach tailored to the usage norms of adolescents expressing negative attitudes toward a cannabis prevention appeal. A multiple-message strategy was implemented-initial unfavorable message evaluations were invalidated using attitudinal rebuttal feedback prior to presenting a third tailored communication. Participants were cannabis-abstinent middle and high school students (ages 11 to 16). Study 1 (N = 808) compared effects of gain- and loss-framed messages tailored to each student’s normative usage perceptions. In Study 2 (N = 391), students were randomly assigned to receive a tailored or non-tailored message after receiving feedback meant to destabilize anti-message attitudes. For at-risk adolescents in Study 1 who perceived cannabis use as normative, a tailored gain-framed message resulted in the lowest usage intentions (p < .05). In Study 2, a conditional multiple-moderated mediation model showed that for high-risk teens with normative beliefs and pro-cannabis attitudes, exposure to a tailored gain-framed communication was associated with decreased cannabis attitude certainty, and lower usage intentions 2 months later (p < .05). Findings have implications for sequential messaging utilization in mass media campaigns and support the efficacy of tailored messages over a one-size-fits-all media approach. Further, results suggest that systematically weakening resistance to persuasive communications and tailoring messages consistent with individually perceived peer norms is an effective prevention strategy.

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