Clinical Takeaway Trauma-focused treatments remain effective for PTSD even when patients report cannabis use alongside co-occurring substance use disorders. Cannabis use does not appear to undermine the clinical benefit of evidence-based, trauma-focused...
Endocannabinoid System Research: Cannabis in Student Mental Health
Clinical Takeaway A mobile app called Minder, co-designed with university students, was tested in a randomized controlled trial to evaluate its impact on mental health and substance use outcomes in a general...
`Endocannabinoid System Research: Athlete Mental Health`
Clinical Takeaway Retired professional athletes from high contact team sports such as football, rugby, and ice hockey face elevated rates of depression, anxiety, and cognitive concerns compared to the general population. Career...
Endocannabinoid System Research: Cannabinoids for Children
Clinical Takeaway Cannabinoids have been studied across a range of pediatric medical conditions, with the current evidence base including both interventional trials and real-world observational data. The strongest and most consistent findings...
`Cannabinoid Clinical Trials: Cannabis for Chronic Back Pain`
Clinical Takeaway In this phase 3 trial of 820 adults with chronic low back pain, the full-spectrum cannabis extract VER-01 was evaluated over a 12-week double-blind period with extended follow-up reaching 15...
Endocannabinoid System: Cannabis for Chronic Pain Evidence
Clinical Takeaway Cannabinoids, particularly products with measurable THC content, show modest but consistent evidence for reducing chronic pain compared to placebo in randomized controlled trials, though the overall certainty of evidence remains...
Change My Mind
Your endocannabinoid system was already mediating pain, mood, and immune function before cannabis became trendy—the plant just happens to be one way to influence it. Further Reading Cannabis NewsRecreational drugs triple the...
Woman Yelling at Cat
When your patient insists cannabis cured their condition without doing the double-blind placebo-controlled trial their anecdote is not, and you have to explain the difference between correlation and causation again. Further Reading...
Tuxedo Winnie the Pooh
“Cannabis is just a plant, can’t be medicine.” Right side fancy Pooh: “Actually, cannabinoids modulate the endocannabinoid system and demonstrate efficacy in peer-reviewed clinical trials for nausea, pain, and seizure disorders.” Further...
Sad Pablo Escobar
When your patient asks if cannabis helps with anxiety but forgets to mention they’re using it to avoid actually addressing their anxiety. Further Reading Cannabis NewsRecreational drugs triple the risk of stroke...