Clinical Takeaway Insomnia before a traumatic event increases the risk of developing posttraumatic stress symptoms, which in turn drives higher rates of alcohol and cannabis use in the weeks and months following...
Endocannabinoid System Research: CBD & Cortical Excitability
Clinical Takeaway In a controlled crossover trial in healthy adults, CBD at both low and high doses showed no direct effect on cortical excitability compared to placebo, suggesting its anti-seizure benefit may...
`Cannabinoid Clinical Trials: Oral Cannabis Effects on Sleep`
Clinical Takeaway In this small pilot trial of 20 adults with diagnosed insomnia disorder, a single oral dose of 10 mg THC combined with 200 mg CBD reduced total sleep time compared...
endocannabinoid system clinical research: Eating & Weight
Clinical Takeaway A 15-year Canadian cohort study tracked adolescents into early adulthood to examine how body image concerns and disordered eating patterns in youth predict later eating disorders, mental health conditions, and...
`Endocannabinoid System Research: Cannabis for PTSD and SUD`
Clinical Takeaway Trauma-focused therapy remains effective for PTSD even in patients who use cannabis, including those with co-occurring substance use disorders. Patients should not be excluded from or delayed in receiving evidence-based...
endocannabinoid system clinical research: Mobile Mental Health
Clinical Takeaway A randomized controlled trial tested the Minder mobile app, co-developed with university students, to address mental health and substance use challenges during the college transition period. Digital tools like this...
endocannabinoid system clinical research athletes mental health
Clinical Takeaway Retired professional athletes from high contact team sports such as football, rugby, and ice hockey show elevated rates of depression, anxiety, and cognitive concerns compared to the general population. Key...
Endocannabinoid System Research: Cannabinoids for Children
Clinical Takeaway Cannabinoids have been studied across a wide range of medical conditions in children under 18, with evidence drawn from interventional trials, observational studies, surveys, and qualitative research. The review is...
`Endocannabinoid System & Cannabis for Chronic Back Pain Trial`
Clinical Takeaway In this phase 3 trial of 820 adults with chronic low back pain, the full-spectrum cannabis extract VER-01 was evaluated against placebo over 12 weeks with extended follow-up periods reaching...
Endocannabinoid System Research: Cannabis for Chronic Pain
Clinical Takeaway Clinical trials show that cannabis-based products, particularly those with higher THC content, provide modest reductions in chronic pain compared to placebo, though the overall strength of evidence remains low to...