Parkinson disease (PD) is a neurodegenerative disorder very common among the older population. Since standard treatments often only partially relieve...
Self-reported Illicit Drug Use Among Norwegian University and College Students: Association with Age, Gender, and Geography
In many Western countries, illicit drug use has been purportedly prevalent among students in higher education, even more so than...
Stress, Emotional Intelligence and the Intention to Use Cannabis in Spanish Adolescence: Influence of COVID-19 confinement
The disease brought about by the SARS-CoV-2, COVID-19 coronavirus has had an unprecedented global impact. Confinement to control the outbreak...
Tetrahydrocannabinol-Rich Extracts From Cannabis Sativa L. Improve Glucose Consumption and Modulate Metabolic Complications Linked to Neurodegenerativ
Tetrahydrocannabinol (THC), a major constituent of the plant cannabis, can interact with endocannabinoid receptors abundant on neurons, thereby affecting multiple...
Association Between Marijuana Use and Cardiovascular Disease in US Adults
The prevalence of marijuana use has risen steadily for the past decade, reaching approximately 200 million consumers worldwide. At the...
Anti-obesity therapy with peripheral CB1 blockers: from promise to safe practice
Pharmacological blockers of the cannabinoid receptor type-1 (CB1) were shown in both research and clinical settings to deliver highly efficient...
Inverse Agonism of Cannabinoid Receptor Type 2 Confers Anti-inflammatory and Neuroprotective Effects Following Status Epileptics
When the brain is attacked by infections, microglia, the immune cells that reside inside and regulate inflammation in the brain,...
Adolescent CB1 receptor antagonism influences subsequent social interactions and neural activity in female rats
The endogenous cannabinoid system (ECS), which consists of endocannabinoids - signalling lipid molecules, cannabinoid receptors CB1 and CB2 that they...
Reduction of Benzodiazepine Use in Patients Prescribed Medical Cannabis
Benzodiazepines constitute a class of medication with sedative properties commonly used as the main treatment for a variety of neurological...
Roles of Cannabinoids in Melanoma: Evidence from In Vivo Studies
Melanoma is a highly metastatic skin cancer with increasing incidence and mortality rate worldwide. In 2018 alone, approximately 280,000 new...