Cannabidiol (CBD) is a component of the plant cannabis with various therapeutic benefits including antidepressant and anxiolytic (anxiety-relieving). Despite being...
Substitution of medical cannabis for pharmaceutical agents for pain, anxiety, and sleep
Until now, medical cannabis remains a highly controversial substance, being condoned in different forms by half of the states but...
The Endocannabinoid System Modulating Levels of Consciousness, Emotions and Likely Dream Contents
The endogenous cannabinoid system is a signaling system of the human body that comprises endocannabinoids (such as anandamide and 2-AG),...
Anti-invasion Effects of Cannabinoids Agonist and Antagonist on Human Breast Cancer Stem Cells
In most types of solid tumors, the metastasis of invasive tumor cells from their origin to different organs throughout the...
The CB1R rs2023239 receptor gene variant significantly affects the reinforcing effects of nicotine, but not cue reactivity, in human smokers
Tobacco smoking is a leading cause of preventable death, yet only one-third of those who try can successfully quit smoking....
Using measured cannabidiol and tetrahydrocannabinol metabolites in urine to differentiate marijuana use from consumption of commercial cannabidiol products
The current method for detection of marijuana use measures 11-nor-carboxy-Δ9-tetrahydrocannabinol (11-COOH-THC), the major metabolite of THC in a person’s urine....
The proposed mechanisms of action of CBD in epilepsy
Cannabidiol (CBD) has demonstrated positive effects against a wide spectrum of seizures. In fact, highly purified CBD has been approved...
Cannabidiol as a novel inhibitor of Id-1 gene expression in aggressive breast cancer cells
Invasion and metastasis of aggressive breast cancer cells to other organs is the final and fatal step during cancer progression....
Safety and Tolerability of Cannabidiol in Parkinson Disease: An Open Label, Dose-Escalation Study
Parkinson disease (PD) is a neurodegenerative disorder very common among the older population. Since standard treatments often only partially relieve...
Self-reported Illicit Drug Use Among Norwegian University and College Students: Association with Age, Gender, and Geography
In many Western countries, illicit drug use has been purportedly prevalent among students in higher education, even more so than...