Abnormal Cannabidiol Affects Production of Pro‐Inflammatory Mediators and Astrocyte Wound Closure in Primary Astrocytic‐Microglial Cocultures In Summary Damage to the brain such as brain trauma or stroke comprises two consecutive events. The...
Neurological and neurodegenerative conditions, physical activities, and the endocannabinoid system – how might all these be linked?
Can physical activity support the endocannabinoid system in the preventive and therapeutic approach to neurological disorders? In Summary The endocannabinoid signaling system (ECS) of the body includes naturally produced chemicals called cannabinoids,...
Urgent need for clinical trials investigating the effects of cannabinoids on hormone receptor-positive breast cancer therapy
Cannabinoids and Hormone Receptor-Positive Breast Cancer Treatment In Summary Breast cancer (BC) is the most common cancer in women worldwide. Approximately 70-80% of BC cases fall into the category of hormone...
Benefits of cannabidiol on skin cells are compromised in psoriasis patients receiving UV irradiation treatment
Cannabidiol Effects on Phospholipid Metabolism in Keratinocytes from Patients with Psoriasis Vulgaris In Summary Endocannabinoid is a group of lipids naturally produced by the body. The endocannabinoid system, which includes mainly endocannabinoids...
Cannabinoid receptor type 2 as a promising new target for schizophrenia drugs
Contribution of CB2 receptors in schizophrenia-related symptoms in various animal models In Summary Schizophrenia is a serious, chronic mental disorder that disrupts how a person thinks, feels and behaves. Its psychotic (also...
Is Cannabis a Valid Treatment for Coronavirus?
Researchers Looking At CBD To Treat COVID-19 Lung Inflammation In Summary As more information comes to light about the severe lung inflammation that seems to be the most dangerous symptom of this...
Activation of a cannabinoid receptor represents a promising therapeutic strategy for Parkinson’s Disease
Activation of CB2R with AM1241 ameliorates neurodegeneration via the Xist/miR-133b-3p/Pitx3 axis In Summary Schematic representation showing the proposed mechanism by which the CBR2 agonist AM1241 exerts neuroprotective effects through the Xist/ miR-133b-3p/Pitx3...
The endocannabinoid system controls various functions of the olfactory circuit
Cannabinoid Control of Olfactory Processes: The Where Matters In Summary: Cannabis exerts its mental and physical effects by producing chemicals called cannabinoids. In mammalian, the endocannabinoid system (ECS) include cannabinoid receptors type...
In chronic cannabis users, reverse cholesterol transport function is particularly important for maintaining general and cognitive health
Chronic marijuana use moderates the correlations of serum cholesterol with systemic mitochondrial function and fluid cognition In Summary Reverse cholesterol transport (RCT) is a crucial biological process, in which excess cholesterol from...
Mediation of the cannabinoid receptor type 1 can enhance the antidepressant powers of conventional therapy
In Summary Depression is one of the most common mood disorders, affecting over 320 million people worldwide; however, an effective medication for this condition is still elusive. Because the pathogenesis of depression...