Activation of CB2R with AM1241 ameliorates neurodegeneration via the Xist/miR-133b-3p/Pitx3 axis In Summary Schematic representation showing the proposed mechanism by which the CBR2 agonist AM1241 exerts neuroprotective effects through the Xist/ miR-133b-3p/Pitx3...
The endocannabinoid system controls various functions of the olfactory circuit
Cannabinoid Control of Olfactory Processes: The Where Matters In Summary: Cannabis exerts its mental and physical effects by producing chemicals called cannabinoids. In mammalian, the endocannabinoid system (ECS) include cannabinoid receptors type...
In chronic cannabis users, reverse cholesterol transport function is particularly important for maintaining general and cognitive health
Chronic marijuana use moderates the correlations of serum cholesterol with systemic mitochondrial function and fluid cognition In Summary Reverse cholesterol transport (RCT) is a crucial biological process, in which excess cholesterol from...
Mediation of the cannabinoid receptor type 1 can enhance the antidepressant powers of conventional therapy
In Summary Depression is one of the most common mood disorders, affecting over 320 million people worldwide; however, an effective medication for this condition is still elusive. Because the pathogenesis of depression...
Citral, a natural activator of the cannabinoid receptor type 2, can help combat pain and inflammatory conditions
Citral Inhibits the Inflammatory Response and Hyperalgesia in Mice: The Role of TLR4, TLR2/Dectin-1, and CB2 Cannabinoid Receptor/ATP-Sensitive K+ Channel Pathways In Summary The endocannabinoid system has long been a target...
Targeting the endocannabinoid system for stroke prevention
Endocannabinoids and Stroke Prevention: Review of Clinical Studies In Summary Ischemic stroke is a very common medical emergency with 15 million new cases worldwide annually. Its consequences are severe, usually causing permanent...
Cannabidiol may enhance the effectiveness of immunotherapy in multiple myeloma
High Expression of Cannabinoid Receptor 2 on Cytokine-Induced Killer Cells and Multiple Myeloma Cells In Summary Multiple myeloma (MM) is a cancer of the plasma cells, and is one of the most...
Dysregulation of Fatty Acid Amide Hydrolase Correlates with Increased Obesity
The influence of the fatty acid amide hydrolase 385C_A single nucleotide polymorphisms on obesity susceptibility In Summary A recent study has revealed the positive correlation of fatty acid amine hydrolase (FAAH) polymorphisms...
More Research on Adolescent Cannabis Use and Mental Disorders
The persistence of the association between adolescent cannabis use and common mental disorders into young adulthood In Summary Further examination of chronic cannabis use in adolescents correlates with a higher prevalence of...
The Possible Effects of Cannabis Use in Adolescent Females
What Every Pediatric Gynecologist Should Know About Marijuana Use in Adolescents In Summary A recent article has called for pediatric gynecologists to ward against the use of cannabis in adolescent females. By...