The fundamental role of the endocannabinoid system in endometrium and placenta: implications in pathophysiological aspects of uterine and pregnancy disorders In Summary The endocannabinoid system (ECS) consists of cannabinoids produced naturally by...
Cannabinoids as promising anti-tumor drugs in prostate cancer
Treatment with Cannabinoids as a Promising Approach for Impairing Fibroblast Activation and Prostate Cancer Progression In Summary Cannabinoids are lipids that can regulate multiple biological processes by interacting with cell-surface cannabinoid receptors,...
The potential application of the cannabinoid Beta-caryophyllene in glioblastoma therapy
Beta-Caryophyllene Inhibits Cell Proliferation through a Direct Modulation of CB2 Receptors in Glioblastoma Cells In Summary Glioblastoma (GBM) is an aggressive type of cancer of the brain and spinal cord, arising from...
Cannabis Sativa Revisited
Crosstalk between microRNA Expression, Inflammation, Oxidative Stress, and Endocannabinoid Response System in Critically Ill Patients with Sepsis In Summary The cannabinoid receptors type 1 (CB1) and type 2 (CB2) can be activated...
Cannabidiol: Attenuation of behavioral and cognitive schizophrenia symptoms leads to potential clinical applications
Cannabidiol attenuates behavioral changes in a rodent model of schizophrenia through 5-HT1A, but not CB1 and CB2 receptors In Summary Although cannabidiol (CBD), a major constituent of the plant cannabis, is known...
The endocannabinoid system mediates the enhanced analgesia and GI safety advantage of a newly developed NSAID derivative
Enhanced Analgesic Effects and GI Safety of A Novel Hydrogen Sulfide‐Releasing Anti‐Inflammatory Drug (ATB‐352): A Role for Endogenous Cannabinoids In Summary Nonsteroidal anti‐inflammatory drugs (NSAIDs) are the preferable alternatives to opioids in...
Complex correlations between selected endocannabinoids measured in blood or semen and sperm quality in Swiss men
Semen endocannabinoids are correlated to sperm quality in a cohort of 200 young Swiss men In Summary Endocannabinoids are lipid-derived signaling molecules generated naturally by our bodies that act on the same...
The use of cannabis for pain management: Potential side effects on myofascial tissues of the musculoskeletal system.
Sensitivity of the Fasciae to the Endocannabinoid System: Production of Hyaluronan-Rich Vesicles and Potential Peripheral Effects of Cannabinoids in Fascial Tissue In Summary Myofascial tissue is a thin, strong, fibrous connective tissue...
The endocannabinoid receptor CB2 is a regulator of trauma-inducing anxiety and a potential target for PTSD drugs
Cannabinoid CB2 receptors mediate the anxiolytic-like effects of monoacylglycerol lipase inhibition in a rat model of predator-induced fear In Summary Researchers recently identified a signaling pathway in the endocannabinoid system that regulates...
The wide distribution of cannabinoid receptors in the gastrointestinal tract suggests cannabinoids like CBD can relieve GI pain
Localization of cannabinoid and cannabinoid related receptors in the cat gastrointestinal tract In Summary Cannabidiol (CBD) is a component of the plant cannabis with great potential for medical applications because of its...