Comparison of the Neurotoxic and Seizure-Inducing Effects of Synthetic and Endogenous Cannabinoids with D9-Tetrahydrocannabinol In Summary Synthetic cannabinoids are commonly used as recreational drugs. However, an increasing number of clinical reports have...
Strong correlation between grey matter volume and striatal glutamate level in the brains of early psychosis patients who used cannabis
Association of cannabis with glutamatergic levels in patients with early psychosis: Evidence for altered volume striatal glutamate relationships in patients with a history of cannabis use in early psychosis In Summary: Psychosis...
The influence of independent or combined cannabis and opioids use on depression and anxiety in weight loss surgery patients
A preliminary study on the influence of cannabis and opioid use on weight loss and mental health biomarkers post weight loss surgery In Summary: The number of people with obesity decided to...
Topical cannabis-based medicines – A novel, effective treatment for non-uremic calciphylaxis leg ulcers
Topical cannabis-based medicines – A novel paradigm and treatment for non-uremic/ calciphylaxis leg ulcers: An open label trial In Summary: Non-Uremic Calciphylaxis (NUC) is a rare condition that manifests as painful, non-healing...
Activation of cannabinoid receptor-2 in spinal cord improves the integrity of the blood–spinal cord barrier and reduces bone cancer pain
Spinal cannabinoid receptor-2 activation reduces hypersensitivity associated with bone cancer pain and improves the integrity of the blood–spinal cord barrier In Summary: Bone cancer pain (BCP) is a severe but common...
Targeting the cannabinoid receptors to regulate blood glucose level and body weight
Influence of Cannabinoid Receptor Deficiency on Parameters Involved in Blood Glucose Regulation in Mice In Summary The pancreas is the organ that produces insulin and its lesser known counterpart, glucagon, both of...
Abnormalities in the endocannabinoid system are associated with common female reproductive disorders
The fundamental role of the endocannabinoid system in endometrium and placenta: implications in pathophysiological aspects of uterine and pregnancy disorders In Summary The endocannabinoid system (ECS) consists of cannabinoids produced naturally by...
Cannabinoids as promising anti-tumor drugs in prostate cancer
Treatment with Cannabinoids as a Promising Approach for Impairing Fibroblast Activation and Prostate Cancer Progression In Summary Cannabinoids are lipids that can regulate multiple biological processes by interacting with cell-surface cannabinoid receptors,...
The potential application of the cannabinoid Beta-caryophyllene in glioblastoma therapy
Beta-Caryophyllene Inhibits Cell Proliferation through a Direct Modulation of CB2 Receptors in Glioblastoma Cells In Summary Glioblastoma (GBM) is an aggressive type of cancer of the brain and spinal cord, arising from...
Cannabis Sativa Revisited
Crosstalk between microRNA Expression, Inflammation, Oxidative Stress, and Endocannabinoid Response System in Critically Ill Patients with Sepsis In Summary The cannabinoid receptors type 1 (CB1) and type 2 (CB2) can be activated...