the week in b weed b february 27 2026

The Week in Weed: February 27, 2026 – Lexology

✦ New
CED Clinical Relevance
#62 Notable Clinical Interest
Emerging findings or policy developments worth monitoring closely.
ResearchTHCSafetyDosingMental Health
Why This Matters
Patients starting cannabis therapy should understand that acute effects, including changes in perception, heart rate, and cognition, are time-limited but real, and knowing what to expect helps reduce anxiety and supports safer, more informed use.
Clinical Summary

Research from the University of Calgary and Washington State University has added to the growing body of evidence examining how cannabis affects the body acutely, with findings pointing to measurable physiological and psychoactive responses following cannabis use. Understanding acute cannabis effects is clinically relevant because these short-term changes inform how patients should be counseled around timing, setting, and dose when initiating or adjusting therapy. The collaboration between Canadian and American research institutions reflects an expanding cross-border scientific effort to characterize cannabis pharmacology with greater rigor.

Dr. Caplan’s Take
“Good cannabis medicine has always required honest conversations about acute effects, and studies like this give clinicians better language and data to have those conversations without either minimizing or catastrophizing what patients will actually feel.”
Clinical Perspective

🔬 This University of Calgary and Washington State University research adds to our growing understanding of cannabis’s acute pharmacological effects, contributing valuable data to the evidence base for clinical decision-making.

🔹 As cannabis becomes increasingly integrated into medical practice, studies examining mechanism of action help us better counsel patients on what to expect and optimize therapeutic outcomes.

🔬 The findings underscore the importance of continued rigorous research to distinguish acute effects from chronic impacts, particularly as we work to standardize dosing and administration in clinical settings.

💬 Join the Conversation

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