Cannabinoid Chewing Gum: Promising Concept, Weak Evidence

There has only been one published placebo-controlled trial investigating cannabinoid chewing gum as a drug delivery systemโ€ฆ both CBD and placebo reduced pain slightly, but there was no significant difference between CBD and placebo on primary outcomes (mean difference in 30-min pain reduction: 0.1 on VAS, 95% CI: [โ€“0.3, 0.5], p = 0.61).

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