✦ New CED Clinical Relevance #72 Notable Clinical Interest Emerging findings or policy developments worth monitoring closely. NeurologyPolicyPediatricsCBD Why This Matters Clinicians treating pediatric drug-resistant epilepsy need to understand current NHS access...
Endocannabinoid System Research: Cannabinoids for Children
Clinical Takeaway Cannabinoids have been studied across a range of pediatric medical conditions, with evidence drawn from interventional trials, observational studies, and surveys. The current body of research supports cautious clinical consideration...
Daily Digest: Last 19 Hours: Aging Brains, Adolescent Risk, and the Slow March of Policy Reform — March 04, 2026
A synthesis of 53 recently added cannabis articles — key themes, clinical context, and Dr. Caplan’s take.
Endocannabinoid System Research: Cannabis & Autism Risk
Clinical Takeaway Children exposed to cannabis during the peripregnancy period showed associations with behavioral and developmental differences in offspring, with effects varying based on whether children had ASD symptoms. These findings suggest...
Cannabidiol for Lennox-Gastaut: Clinical Trial Evidence
Clinical Takeaway Pharmaceutical-grade cannabidiol (Epidiolex) reduced drop seizure frequency in Lennox-Gastaut syndrome patients at thresholds below the traditional 50% benchmark, with caregiver-reported outcomes confirming that even smaller reductions translated to meaningful real-world...
Cannabinoid Clinical Trials: CBD Gel Safety in Fragile X
Clinical Takeaway Transdermal cannabidiol gel (ZYN002) has demonstrated an acceptable long-term safety and tolerability profile in children and adolescents with Fragile X syndrome across an ongoing open-label extension study. The treatment targets...
Endocannabinoid System Research: Cannabis for Autism
Clinical Takeaway Across randomized clinical trials, cannabis derivatives and their analogs showed promising early signals for improving core and associated symptoms of autism spectrum disorder, including social communication and behavioral challenges. The...
Cannabinoids for Pediatric Care: Evidence-Based Clinical Review
Clinical Takeaway Pediatric cannabinoid research is an active and growing field, with 276 studies identified across multiple designs, reflecting real-world clinical use across a range of medical conditions in children under 18....
Children’s National Hospital sees more cannabis addiction among teens and tweens – WTOP News
✦ New CED Clinical Relevance #75 Strong Clinical Relevance High-quality evidence with meaningful patient or clinical significance. PediatricsMental HealthTHCSafetyResearch Why This Matters Clinicians need to recognize that modern cannabis products contain significantly...
Endocannabinoid System Research: Cannabinoids for Children
Clinical Takeaway Cannabinoids have been studied across a range of pediatric medical conditions, with the current evidence base drawing from over 270 studies including both interventional and observational designs. The available data...