Clinical Takeaway Transdermal cannabidiol gel (ZYN002) has been studied in children and adolescents with Fragile X syndrome through an open-label extension trial focused on long-term safety and tolerability. Early interim data suggest...
Endocannabinoid System Research: Cannabis & Autism Review
Clinical Takeaway Cannabinoid-based treatments, including CBD-rich preparations, have shown preliminary benefits for certain autism-related symptoms such as irritability, hyperactivity, and sleep difficulties in clinical trial data. The evidence base remains limited in...
Daily Digest: Last 48 Hours: Adolescent Risk, Aging Brains, and the Long Road to Pharmaceutical-Grade Cannabis — March 04, 2026
A synthesis of 53 recently added cannabis articles — key themes, clinical context, and Dr. Caplan’s take.
Daily Digest: Last 24 Hours: Adolescent Risk, Aging Brains, and the Slow March Toward Pharmaceutical-Grade Cannabis — March 04, 2026
Last 24 Hours March 04, 2026 — 41 articles reviewed This cycle’s coverage clustered around two poles of the age spectrum, with a single study in Pediatrics reinforcing that even infrequent adolescent...
Daily Digest: Last 9 Hours: Cognitive Safety Signals, Adolescent Risk, and the Regulatory Puzzle That Still Defines Cannabis Medicine — March 03, 2026
A synthesis of 14 recently added cannabis articles — key themes, clinical context, and Dr. Caplan’s take.
Endocannabinoid System: Cannabis Use & Child Development
Clinical Takeaway Maternal cannabis use during the peripregnancy period was associated with behavioral and developmental differences in children, with effects varying depending on whether the child showed symptoms of autism spectrum disorder....
Cannabidiol for Lennox-Gastaut: Clinical Trial Evidence
Clinical Takeaway Plant-derived cannabidiol (CBD) oral solution produced meaningful reductions in drop seizures in patients with Lennox-Gastaut syndrome at thresholds below the conventional 50% benchmark used in clinical trials. Caregiver-reported outcomes aligned...
Cannabinoids for Autism: Clinical Evidence & ASD Research
Clinical Takeaway Several randomized clinical trials have examined cannabis derivatives, including CBD-rich preparations, for core and associated symptoms of autism spectrum disorder, with findings suggesting potential benefits for behavioral challenges, anxiety, and...
`Cannabinoids for Children: Clinical Evidence Reviewed`
Clinical Takeaway Current evidence on cannabinoids in pediatric patients spans 276 studies across multiple designs, capturing both plant-derived and pharmaceutical formulations used to treat medical conditions in children under 18. The research...
Study Published in Pediatrics Finds Infrequent Cannabis Use Can Impact Adolescent …
✦ New CED Clinical Relevance #78 Strong Clinical Relevance High-quality evidence with meaningful patient or clinical significance. PediatricsMental HealthResearchSafety Why This Matters Clinicians should counsel adolescent patients and parents that even infrequent...