Although incident off-label oral cannabinoid use was relatively low among all older Ontarian adults, this drug class was used with greater frequency and more often in potentially concerning ways among older adults with COPD.
Older Adults and Medical Cannabis: Promising Interest, Scarce Evidence
Evidence of efficacy for relief of an array of symptoms is overall scanty, and almost all study participants are aged < 60 years. The risk of known and potential adverse effects is considerable, with concerns for cognitive, cardiovascular and gait and stability effects in older adults.
Older Adults on Prescribed Cannabis Report Well-Being Gains, But Study Cannot Rule Out Placebo or Natural Recovery
Older aged individuals experience considerable improvement in health and well-being when prescribed cannabis-based medicinal products — though these findings come from an observational registry without a comparator arm, meaning improvement cannot be attributed solely to the intervention.
Older Adults on Cannabis and Interacting Drugs Face Elevated Intoxication Risk, Study Finds
The risk of drug-related intoxication was 2.61 (95% CI 1.42–4.79) amongst 3,926 patients exposed to cannabis and DNTI compared to 12,223 controls, suggesting that prescribing practices for cannabis may not adequately consider the implications of concomitant interacting medications.
Cannabis Medicines Cause Dose-Dependent Side Effects in Older Adults, Meta-Analysis Finds
THC dose-dependently increased the incidence of dry mouth, dizziness/lightheadedness, mobility/balance/coordination difficulties, dissociative/thinking/perception problems and somnolence/drowsiness.
Older Adults Using Cannabis for Sleep Differ in Patterns From Other Cannabis Users, Small Clinic Survey Finds
Among cannabis users in our sample, 29% reported using cannabis for sleep disturbance. They were more likely than other users to be female (p=.07), consume cannabis more frequently (p=.01), use products containing THC (vs. CBD-only; p<.01), and use cannabis to target more symptoms (p<.01).
Older Adults with COPD Were Prescribed Synthetic Cannabinoids More Often—and at Higher Doses—Than Those Without the Disease
Incident synthetic oral cannabinoid use during this period occurred with significantly greater frequency among older adults with COPD (0.6%) versus older adults without COPD (0.3%), and those with COPD used these drugs for significantly longer durations and more frequently at higher doses.
Cannabis use, cognitive function and dementia risk in older adults: observational and genetic analyses.
The cognitive effects of cannabis use in older adults remain unclear, despite increasing use for medical and recreational purposes in this age group. To inve…