Although cannabinoid-based medications were generally safe and acceptable to adults aged over 50 years, these estimates are limited by the lack of a control condition and considerable heterogeneity. Nevertheless, they complement and are consistent with comparable evidence from randomised controlled trials.
Acupuncture May Ease Non-Motor Parkinson’s Symptoms, but Evidence Remains Uncertain
The results of the analysis suggested that acupuncture treatment could ameliorate the symptoms of depression, quality of life, cognition, total mentation, behaviour and mood, and activities of daily living in PD patients. Nevertheless, more prospective, well-designed RCTs with larger sample sizes are required to confirm our findings.
Common But Manageable: What a 58-Trial Meta-Analysis Reveals About Cannabis Medicine Side Effects in Older Adults
Although CBMs in general are safe and acceptable in middle aged and older adults, one needs to be mindful of certain common dose-dependent side-effects of THC-containing CBMs.
Citalopram Shows Modest Benefit for Dementia Agitation; Trazodone Linked to Higher Adverse Events
Among the antidepressant drugs included in this study, treatment with citalopram was probably the only optimal intervention, when considering the improvement from baseline to the end of the intervention, and there was not a statistically significant difference in safety when compared with a placebo treatment.
Cannabis Medicines Appear Broadly Tolerated in Adults Over 50, But Key Uncertainties Remain
Although cannabinoid-based medications were generally safe and acceptable to adults aged over 50 years, these estimates are limited by the lack of a control condition and considerable heterogeneity. Nevertheless, they complement and are consistent with comparable evidence from randomised controlled trials.
Cannabis Medicines Cause Dose-Dependent Side Effects in Older Adults, Meta-Analysis Finds
THC dose-dependently increased the incidence of dry mouth, dizziness/lightheadedness, mobility/balance/coordination difficulties, dissociative/thinking/perception problems and somnolence/drowsiness.
Only Citalopram Shows Significant Benefit for Dementia Agitation Among Antidepressants, Network Meta-Analysis Finds
Among the antidepressant drugs included in this study, treatment with citalopram was probably the only optimal intervention, when considering the improvement from baseline to the end of the intervention, and there was not a statistically significant difference in safety when compared with a placebo treatment.
Prevalence of schizophrenia spectrum and bipolar disorder among patients with cannabis induced psychosis: a systematic review and meta-analysis.
Distinguishing cannabis-induced psychosis from primary psychiatric disorders is difficult and has significant clinical and prognostic implications. Current t…
Therapeutic Use of Cannabis and Cannabinoids: A Review.
Approximately 27% of adults in the US and Canada report having ever used cannabis for medical purposes. An estimated 10.5% of the US population reports using…
Impact of Preoperative Cannabis use on Clinical Outcomes of Spinal Fusion – Systematic Review and Meta-analysis.
Systematic review and meta-analysis. To explore the impact of preoperative cannabis use on perioperative outcomes of spinal fusion procedures. of background …