WHY IT MATTERS: Patients in Brazil and those watching international cannabis policy should know that new domestic cultivation rules could meaningfully expand access to locally produced, regulated cannabis medicines, potentially lowering costs and improving product consistency. CLINICAL OVERVIEW: Brazil’s updated cannabis regulatory framework represents a significant shift toward integrating medical cannabis into the formal healthcare system, including provisions for domestic cultivation under health authority oversight. The framework addresses THC-containing products more explicitly, which has direct implications for how physicians can recommend and patients can access a broader range of cannabinoid formulations.