WHY IT MATTERS: If you use cannabis daily and experience recurring episodes of severe vomiting that hot showers seem to relieve, you should discuss cannabinoid hyperemesis syndrome with your physician before your next emergency room visit. CLINICAL OVERVIEW: Cannabinoid hyperemesis syndrome is a paradoxical condition in which heavy, long-term cannabis use causes cyclical episodes of severe nausea, vomiting, and abdominal pain, often relieved temporarily by hot showers or baths. The syndrome is thought to involve dysregulation of cannabinoid receptors in the gut and hypothalamus, particularly with chronic high-potency THC exposure, though the precise mechanism remains under active investigation.