Cannabis exerts fascinating biphasic effects on the brain, stimulating neural activity in the short term while triggering compensatory adaptations during chronic use. Recent findings from JAMA Psychiatry reveal reduced synaptic density in chronic users, challenging the idea that cannabis is solely neuroplastic. Understanding this dual nature offers critical insights into balancing therapeutic benefits with long-term risks.
In chronic cannabis users, reverse cholesterol transport function is particularly important for maintaining general and cognitive health
Chronic marijuana use moderates the correlations of serum cholesterol with systemic mitochondrial function and fluid cognition In Summary Reverse cholesterol transport (RCT) is a crucial biological process, in which excess cholesterol from...
Blunted highs: Cannabis tolerance behavioral models and pharmacodynamics
Chronic daily cannabis use builds tolerance to some but not all of the effects of cannabis With the increase of cannabis legalization, chronic cannabis use is expected to rise in the coming...