✦ New CED Clinical Relevance #70Notable Clinical Interest Emerging findings or policy developments worth monitoring closely. ⚒ Cannabis News | CED Clinic Cannabis Use DisorderCb1 ReceptorAddiction MedicinePharmaceutical DevelopmentWithdrawal Why This MattersAelis Farma is developing AEF0117, a...
This narrative review examines whether the endocannabinoid system may play a biochemical role in ADHD pathophysiology. It gathers 11 preclinical and 2 clinical studies and argues that ECS signaling may intersect with attention, impulsivity, and hyperactivity pathways. The core limitation is that the evidence remains thin, heavily preclinical, and far from proving that cannabinoid-based treatments are ready for clinical use in ADHD.
Loss of dystrophin reduces CB1 receptor expression and endocannabinoid-dependent synaptic plasticity in the cerebellar cortex.
Duchenne Muscular Dystrophy (DMD) is a debilitating degenerative condition with complex musculoskeletal and cognitive symptoms. The protein responsible, dyst…
Activation of Cannabinoid Receptor 1 Enhances Wound Healing by Promoting the Proliferative Phase.
The mechanisms underlying wound healing mediated by cannabinoid receptor 1 (CB1)-known for its neuromodulatory functions-remain incompletely understood. Ther…
Targeting mechanosensitive cannabinoid receptor 1 with isoflavone prodrugs attenuates atherosclerotic endothelial dysfunction.
Despite therapeutic advances, atherosclerosis remains a major global health challenge. Most current treatments target systemic risk factors rather than the d…
Bridging reward and resilience: the endocannabinoid system as a unifying mechanism in exercise-induced protection against major depressive disorder.
Major depressive disorder (MDD) refers to a complex mental disorder defined by hindered reward system and hindered stress resilience. The limitations of trad…
5 Alarming Truths About Cannabis and Heart Health
In the age of legalization, cannabis is stepping into the spotlight—but its cardiovascular effects are still under-discussed. While some compounds like CBD show promise, others, like THC and synthetic cannabinoids, pose serious risks to heart health. This blog peels back the layers of science and sentiment to deliver an honest look at how cannabis interacts with the most vital organ in your body.