Among the antidepressant drugs included in this study, treatment with citalopram was probably the only optimal intervention, when considering the improvement from baseline to the end of the intervention, and there was not a statistically significant difference in safety when compared with a placebo treatment.
Cannabis-Based Spray Shown Feasible and Safe for Alzheimer’s Agitation in UK Care Homes
Despite significant COVID-19 pandemic-related challenges, administering nabiximols through oral mucosa to advanced Alzheimer’s patients with agitation demonstrated feasibility and safety. These findings support a larger confirmatory efficacy trial.
Only Citalopram Shows Significant Benefit for Dementia Agitation Among Antidepressants, Network Meta-Analysis Finds
Among the antidepressant drugs included in this study, treatment with citalopram was probably the only optimal intervention, when considering the improvement from baseline to the end of the intervention, and there was not a statistically significant difference in safety when compared with a placebo treatment.
Cannabis-Based Spray Shows Early Safety Promise for Alzheimer’s Agitation—But Proof of Efficacy Still Awaited
Despite significant COVID-19 pandemic-related challenges, administering nabiximols through oral mucosa to advanced Alzheimer’s dementia patients with agitation demonstrated feasibility and safety. These findings support a larger confirmatory efficacy trial.
Assessment of clinical factors that predict response to nabilone for agitation in Alzheimer’s disease: A post hoc analysis of a randomized placebo-controlled trial.
Previously, nabilone showed a medium effect size for treating agitation in moderate-to-severe Alzheimer’s disease (AD), but response varied. These post hoc a…