Top items from the CED news pipeline.
Daily Digest 2026-03-07
✦ New Top items from the CED news pipeline. (82) Scientists are raising new concerns about marijuana use in teens – KPBSResearch continues to build a concerning picture around adolescent cannabis use...
Daily Digest 2026-03-07
✦ New Top items from the CED news pipeline. (82) Scientists are raising new concerns about marijuana use in teens – KPBSResearch continues to build a concerning picture around adolescent cannabis use...
Cannabinoid Clinical Trials: Cannabis Intervention in Teens
Clinical Takeaway Tailored cannabis prevention messaging that first addresses and refutes adolescents’ negative reactions to anti-cannabis appeals, then delivers a third targeted communication, shows promise as a more effective approach than one-size-fits-all...
Study Published in Pediatrics Finds Infrequent Cannabis Use Can Impact Adolescent …
WHY IT MATTERS: Parents and teens should understand that occasional cannabis use is not a safe middle ground during adolescence, as even infrequent exposure appears linked to real academic and emotional consequences. CLINICAL OVERVIEW: Research published in Pediatrics reinforces longstanding clinical concern that adolescent cannabis exposure does not require heavy or daily use to produce measurable harm. Even low-frequency use, occurring as rarely as once monthly, appears associated with worse academic outcomes and disruptions in emotional regulation and mental health.
DPH Commissioner goes ‘On the Record’ about measles outbreaks, cannabis – YouTube
WHY IT MATTERS: If state health authorities move forward with potency restrictions or new labeling requirements, patients who rely on higher-concentration products for legitimate medical purposes may face reduced access or need to significantly adjust their dosing strategies. CLINICAL OVERVIEW: Public health officials are raising concerns about the increasing potency of cannabis products available in the legal market, particularly regarding exposure among adolescents and young people. The discussion centers on how THC concentrations in modern products differ substantially from those in cannabis consumed decades ago, and what that means for developing brains.
The association between cannabis use and brain reward anticipation: a 12-month … – Nature
WHY IT MATTERS: If you or someone you care for uses cannabis regularly and has concerns about mood, motivation, or mental health, this emerging research on reward brain circuitry underscores why timing, potency, and age of first use are factors worth discussing openly with a knowledgeable clinician. CLINICAL OVERVIEW: The endocannabinoid system plays a central role in regulating reward circuitry, and THC directly modulates dopaminergic signaling in ways that can alter how the brain anticipates and responds to rewarding stimuli. This is particularly relevant during adolescence and young adulthood, when reward-related neural networks are still developing and may be more vulnerable to disruption from exogenous cannabinoids.
Lynn Silver, MD, MPH, FAAP, warns of psychiatric risks with adolescent cannabis use
WHY IT MATTERS: Parents and young people should understand that cannabis use during adolescence is not a low-stakes decision, because the developing brain processes cannabinoids very differently than an adult brain does, with potential consequences for long-term mental health. CLINICAL OVERVIEW: Adolescent cannabis use carries meaningful psychiatric risks because the developing brain, particularly the endocannabinoid system, is uniquely vulnerable to disruption from exogenous cannabinoids during the years of active neurodevelopment that extend into the mid-twenties. Exposure during this window has been associated with increased rates of anxiety, depression, and psychosis, with higher-potency THC products amplifying these concerns considerably.
Lynn Silver, MD, MPH, FAAP, warns of psychiatric risks with adolescent cannabis use
WHY IT MATTERS: Teenagers and parents should know that cannabis use during adolescence is not simply a lifestyle choice but a neurological exposure that may meaningfully increase the risk of serious, lifelong psychiatric conditions. CLINICAL OVERVIEW: Adolescent cannabis use carries meaningful psychiatric risk, particularly for conditions like psychosis and bipolar disorder, during a developmental window when the brain is especially vulnerable to THC’s effects on dopaminergic and endocannabinoid signaling. The association between early cannabis exposure and a doubling of risk for these disorders reflects both biological susceptibility and the potency of today’s high-THC products compared to earlier decades.