Clinical Takeaway In this pilot randomized controlled trial of 20 adults with diagnosed insomnia, a single oral dose of 10 mg THC combined with 200 mg CBD actually reduced total sleep time...
endocannabinoid system clinical research eating disorders
Clinical Takeaway The REAL 2.0 study followed Canadian youth for 15 years to examine how adolescent risk factors like body image concerns and disordered eating contribute to mental health and substance use...
Endocannabinoid System Research: Cannabis and PTSD Care
Clinical Takeaway Trauma-focused treatments remain effective for PTSD even when patients report cannabis use alongside co-occurring substance use disorders. Cannabis use does not appear to undermine the clinical benefit of evidence-based, trauma-focused...
Endocannabinoid System Research: Cannabis in Student Mental Health
Clinical Takeaway A mobile app called Minder, co-designed with university students, was tested in a randomized controlled trial to evaluate its impact on mental health and substance use outcomes in a general...
`Endocannabinoid System Research: Athlete Mental Health`
Clinical Takeaway Retired professional athletes from high contact team sports such as football, rugby, and ice hockey face elevated rates of depression, anxiety, and cognitive concerns compared to the general population. Career...
Endocannabinoid System Research: Cannabinoids for Children
Clinical Takeaway Cannabinoids have been studied across a range of pediatric medical conditions, with the current evidence base including both interventional trials and real-world observational data. The strongest and most consistent findings...
`Cannabinoid Clinical Trials: Cannabis for Chronic Back Pain`
Clinical Takeaway In this phase 3 trial of 820 adults with chronic low back pain, the full-spectrum cannabis extract VER-01 was evaluated over a 12-week double-blind period with extended follow-up reaching 15...
Endocannabinoid System: Cannabis for Chronic Pain Evidence
Clinical Takeaway Cannabinoids, particularly products with measurable THC content, show modest but consistent evidence for reducing chronic pain compared to placebo in randomized controlled trials, though the overall certainty of evidence remains...
`Endocannabinoid System & PTSD: Cannabis Meta-Analysis`
Clinical Takeaway People with PTSD and co-occurring substance use disorders who use cannabis can still benefit meaningfully from trauma-focused treatments. Cannabis use does not appear to prevent or significantly undermine the effectiveness...
endocannabinoid system clinical research: Mobile Mental Health RCT
Clinical Takeaway A randomized controlled trial tested the Minder mobile app, co-developed with university students, to address mental health and substance use during a high-risk transitional period. Digital tools like this are...