Clinical Takeaway Topical cannabis balms were tested in a randomized trial for postmenopausal breast cancer patients experiencing joint pain and stiffness caused by aromatase inhibitor therapy. The study evaluated whether this approach...
Cannabinoid Clinical Trials: Cannabis Effects on Alcohol Urge
Clinical Takeaway People who use alcohol heavily and cannabis regularly show different responses to cannabis depending on their working memory capacity, meaning the brain’s ability to hold and process information temporarily. In...
Endocannabinoid System Research: Cannabis Use in Pregnancy
Clinical Takeaway Children born to mothers who used cannabis during pregnancy showed a modestly elevated risk of autism spectrum disorder and a smaller increase in risk of ADHD, based on a pooled...
Endocannabinoid System Research: Cannabis & Autism Review
Clinical Takeaway Cannabinoid-based treatments, including CBD-rich preparations, have shown preliminary benefits for certain autism-related symptoms such as irritability, hyperactivity, and sleep difficulties in clinical trial data. The evidence base remains limited in...
Endocannabinoid System Research: Cannabis & Teen Mental Health
Clinical Takeaway Adolescents with higher levels of depression and anxiety symptoms were more likely to initiate and use cannabis more frequently over the following 18 months. This longitudinal evidence supports the self-medication...
Adolescent Cannabis Use and Psychotic Disorder Risk
Clinical Takeaway Adolescent cannabis use is associated with significantly increased risk of developing psychotic, bipolar, depressive, and anxiety disorders in adolescence and young adulthood, based on large-scale longitudinal population data. These findings...
Endocannabinoid System & Trauma Sleep Research Findings
Clinical Takeaway Insomnia before a traumatic event increases the risk of developing posttraumatic stress symptoms, which in turn drives higher rates of alcohol and cannabis use in the weeks and months following...
Endocannabinoid System Research: CBD & Cortical Excitability
Clinical Takeaway In a controlled crossover trial in healthy adults, CBD at both low and high doses showed no direct effect on cortical excitability compared to placebo, suggesting its anti-seizure benefit may...
`Cannabinoid Clinical Trials: Oral Cannabis Effects on Sleep`
Clinical Takeaway In this small pilot trial of 20 adults with diagnosed insomnia disorder, a single oral dose of 10 mg THC combined with 200 mg CBD reduced total sleep time compared...
endocannabinoid system clinical research: Eating & Weight
Clinical Takeaway A 15-year Canadian cohort study tracked adolescents into early adulthood to examine how body image concerns and disordered eating patterns in youth predict later eating disorders, mental health conditions, and...