Clinical Takeaway GLP-1 receptor agonists showed measurable effects on risk for several common mental health conditions in this Mendelian randomization analysis, suggesting these medications may influence psychiatric outcomes beyond their metabolic effects....
Medical Cannabis Evidence-Based Care: CBD Autism RCT
Clinical Takeaway In a small randomized crossover trial, autistic children aged 5 to 12 received weight-based CBD oil dosing over 12-week periods, allowing researchers to directly compare CBD against placebo within the...
`Cannabinoid Clinical Trials: Cannabis Interventions for Teens`
Clinical Takeaway Scare-tactic cannabis prevention campaigns often fail because teens hold widely different beliefs about the drug, and a one-size-fits-all message rarely lands. This research tested a smarter approach: when a teen...
Endocannabinoid System: Cannabis & Maternal Cytokines
Clinical Takeaway Cannabis use during pregnancy is linked to measurable suppression of key immune signaling proteins (cytokines) in the mother’s bloodstream. Because these cytokines play a critical role in supporting a healthy...
Medical Cannabis for Anxiety & Tourette: Clinical Evidence
Clinical Takeaway Cannabinoid formulations, particularly those containing CBD alone or in combination with THC, show measurable reductions in anxiety symptoms across multiple anxiety-related disorders, including Tourette syndrome, based on pooled clinical trial...
`Cannabinoid Clinical Trials: CBD Doping Risk in Athletes`
Clinical Takeaway Daily use of a broad-spectrum CBD supplement containing trace amounts of other cannabinoids can result in urine concentrations of WADA-prohibited substances, a risk that increases with exercise. Athletes using CBD...
Topical Cannabis for AIMSS: Cannabinoid Clinical Trial
Clinical Takeaway This small randomized trial tested whether topical cannabis balms were feasible and tolerable for managing joint pain and stiffness caused by aromatase inhibitors in postmenopausal breast cancer patients. The study...
Endocannabinoid System & Teen Mental Health Risk Factors
Clinical Takeaway Adolescents with depression, generalized anxiety, social anxiety, and panic symptoms were more likely to initiate and increase cannabis use over an 18-month follow-up period. This longitudinal evidence supports the self-medication...
endocannabinoid system clinical research: Trauma, Sleep & Cannabis Use
Clinical Takeaway People who struggle with sleep problems before experiencing a trauma may be more likely to turn to alcohol or cannabis in the weeks and months following that trauma. This research...
Cannabinoid Clinical Trials: EEG Sleep Insomnia RCT
Clinical Takeaway In this small pilot trial of 20 adults with diagnosed insomnia disorder, a single oral dose of 10 mg THC combined with 200 mg CBD reduced total sleep time compared...