Clinical Takeaway GLP-1 receptor agonists, the drug class that includes medications like semaglutide, were studied for their potential causal effects on ten common mental health conditions using genetic analysis data. The findings...
Cannabinoid Clinical Trials: Cannabis Intervention in Teens
Clinical Takeaway Tailored cannabis prevention messaging that first addresses and refutes adolescents’ negative reactions to anti-cannabis appeals, then delivers a third targeted communication, shows promise as a more effective approach than one-size-fits-all...
Endocannabinoid System & Maternal Cytokines: Clinical Research
Clinical Takeaway Cannabis use during pregnancy is associated with measurable suppression of key immune signaling proteins (cytokines) in the mother’s bloodstream, findings confirmed through urine-verified exposure. Because the immune system plays a...
`Cannabinoid Clinical Trials: Cannabis-Induced Psychosis Risk`
Clinical Takeaway A significant portion of patients diagnosed with cannabis-induced psychosis go on to develop a primary psychiatric disorder such as schizophrenia spectrum disorder or bipolar disorder. Clinicians should treat cannabis-induced psychosis...
Cannabinoid Formulations for Anxiety and Tourette Syndrome
Clinical Takeaway Cannabinoid formulations, particularly CBD-containing products, show measurable reductions in anxiety symptoms across multiple study designs, though effect sizes and optimal dosing vary by condition and formulation. Evidence for Tourette syndrome...
Endocannabinoid System Research: Cannabis & HIV Smoking
Clinical Takeaway Digital therapeutics tailored to people living with HIV show promising feasibility and acceptability as a scalable approach to smoking cessation in this high-risk population. Tobacco use remains a leading driver...
Topical Cannabis Balms for AIMSS: Clinical Trial Data
Clinical Takeaway Topical cannabis balms were tested in a randomized, open-label trial among postmenopausal women with hormone receptor-positive breast cancer who developed musculoskeletal pain and joint stiffness from aromatase inhibitor therapy. The...
Endocannabinoid System Research: Cannabis for Autism
Clinical Takeaway Across randomized clinical trials, cannabis derivatives and their analogs showed promising early signals for improving core and associated symptoms of autism spectrum disorder, including social communication and behavioral challenges. The...
Endocannabinoid System & Teen Mental Health: Clinical Evidence
Clinical Takeaway Adolescents with higher levels of depression and anxiety symptoms were more likely to initiate and use cannabis more frequently over the following 18 months, supporting the idea that young people...
Adolescent Cannabis Use: Mental Health Risks Examined
Clinical Takeaway Adolescent cannabis use is associated with significantly increased risk of developing psychotic, bipolar, depressive, and anxiety disorders in adolescence and young adulthood, based on large-scale longitudinal population data. These findings...