Clinical Takeaway Retired professional athletes from high contact team sports such as football, rugby, and ice hockey face elevated rates of depression, anxiety, and cognitive concerns compared to the general population. Key...
Cannabinoids for Children: Medical Evidence Reviewed
Clinical Takeaway Cannabinoids have been studied across a wide range of pediatric medical conditions, with the current evidence base drawing from hundreds of studies including clinical trials and observational data. The strongest...
endocannabinoid system clinical research: Cannabis for Back Pain
Clinical Takeaway In this phase 3 randomized controlled trial of 820 adults, the full-spectrum cannabis extract VER-01 was evaluated against placebo over 12 weeks for chronic low back pain, with longer-term follow-up...
`Cannabidiol & Cortical Excitability: Clinical Trial Findings`
Clinical Takeaway In this randomized, double-blind, placebo-controlled crossover trial in healthy adults, neither a low nor a high single dose of CBD produced measurable changes in cortical excitability compared to placebo. This...
Cannabinoid Clinical Trials: EEG Sleep Insomnia RCT
Clinical Takeaway In this small pilot trial of 20 adults with diagnosed insomnia disorder, a single oral dose of 10 mg THC combined with 200 mg CBD reduced total sleep time compared...
endocannabinoid system anxiety: Cannabis Flower vs Edibles
Clinical Takeaway Cannabis use for anxiety produced daily reductions that differed based on whether people used flower or edible products, and the balance of THC versus CBD in the product mattered for...
`Cannabidiol for Fibromyalgia: Evidence-Based Cannabis Care`
Clinical Takeaway In this randomized, double-blind, placebo-controlled trial, CBD did not demonstrate superiority over placebo in reducing pain among patients with fibromyalgia. These findings add to the limited and mixed evidence base...
endocannabinoid system clinical research: Eating Disorders
Clinical Takeaway The REAL 2.0 study followed Canadian youth for 15 years to track how adolescent risk factors like body image concerns and disordered eating relate to mental health and substance use...
`Cannabinoid Clinical Trials: Cannabis, PTSD and Substance Use`
Clinical Takeaway People with PTSD and co-occurring substance use disorders who also use cannabis can still benefit meaningfully from trauma-focused treatments. Clinicians should not withhold or delay evidence-based PTSD care based on...
`Endocannabinoid System Research: Cannabis in Mental Health Care`
Clinical Takeaway A randomized controlled trial tested the Minder mobile app, co-developed with university students, to address mental health and substance use during the high-risk college transition period. Digital tools like this...