Clinical Takeaway Cannabis use was associated with daily reductions in anxiety, but the effects varied meaningfully depending on whether participants used flower or edible products and the cannabinoid profile (CBD, THC, or...
cannabinoid clinical trials: CBD vs Placebo Fibromyalgia
Clinical Takeaway In this randomized, double-blind, placebo-controlled trial, CBD did not demonstrate superiority over placebo in reducing pain among patients with fibromyalgia. The findings do not support CBD as an effective standalone...
Endocannabinoid System Clinical Research: REAL 2.0 Findings
Clinical Takeaway The REAL 2.0 study tracked Canadian youth over 15 years to examine how early adolescent factors like body image concerns and disordered eating patterns influence mental health, eating disorders, and...
`Cannabinoids for PTSD and Substance Use: Clinical Evidence`
Clinical Takeaway People who use cannabis and have both PTSD and a substance use disorder still benefit meaningfully from trauma-focused treatments, with outcomes comparable to those who do not use cannabis. This...
endocannabinoid system clinical research: mobile mental health
Clinical Takeaway A randomized controlled trial tested the Minder mobile app, co-developed with university students, to address mental health and substance use during the high-risk transition into university life. Digital tools like...
`Cannabinoids & Athlete Mental Health: Clinical Evidence`
Clinical Takeaway Retired professional athletes from high contact team sports face elevated rates of depression, anxiety, and cognitive concerns compared to the general population, with career-ending injuries, concussion history, and abrupt transition...
Cannabinoids in Pediatric Care: Clinical Evidence Review
Clinical Takeaway Cannabinoids have been studied across a wide range of pediatric medical conditions, with the current evidence base drawing from over 270 studies including both interventional and observational designs. The data...
`Cannabinoid Clinical Trials: Cannabis for Chronic Back Pain`
Clinical Takeaway In this phase 3 trial of 820 adults, the full-spectrum cannabis extract VER-01 was evaluated against placebo over 12 weeks for chronic low back pain, with longer-term follow-up extending to...
Cannabinoid Clinical Trials: CBD Cortical Excitability Study
Clinical Takeaway In a controlled crossover trial of 25 healthy males, CBD at both low and high single doses showed no direct effect on cortical excitability compared to placebo, suggesting CBD alone...
Cannabinoid Clinical Trials: EEG Sleep Insomnia RCT
Clinical Takeaway In this small pilot trial of 20 insomnia patients, a single oral dose of 10 mg THC combined with 200 mg CBD reduced total sleep time compared to placebo, suggesting...