Clinical Takeaway Cannabis use for anxiety relief shows meaningful differences depending on product type, with flower and edible formulations producing distinct day-to-day and longer-term changes in anxiety levels over 30 days. CBD-containing...
`Cannabinoid Clinical Trials: CBD for Fibromyalgia`
Clinical Takeaway In this randomized, double-blind, placebo-controlled trial, CBD did not demonstrate superiority over placebo in reducing pain among patients with fibromyalgia. These findings highlight the gap between widespread patient use of...
`Endocannabinoid System Research: Adolescent Eating & Mental Health`
Clinical Takeaway Eating disorders and disordered body image in adolescence are linked to lasting mental health and substance use challenges into early adulthood. This 15-year Canadian cohort study tracked these trajectories to...
Cannabinoid Clinical Trials: PTSD and Substance Use Meta-Analysis
Clinical Takeaway People with PTSD and co-occurring substance use disorders who use cannabis can still benefit meaningfully from trauma-focused treatments. Cannabis use does not appear to prevent evidence-based PTSD therapies from working,...
endocannabinoid system clinical research: Mobile Mental Health
Clinical Takeaway A randomized controlled trial tested the Minder mobile app, co-developed with university students, to address mental health and substance use during the high-risk college transition period. Digital tools like this...
`Cannabinoid Clinical Trials in Athlete Mental Health`
Clinical Takeaway Retired professional athletes from high contact team sports such as football, rugby, and hockey face elevated rates of depression, anxiety, and cognitive concerns compared to the general population, with symptoms...
Cannabinoids in Pediatric Care: Clinical Evidence Review
Clinical Takeaway Cannabinoids have been studied across a range of pediatric medical conditions, with the current evidence base drawing from over 270 studies including both interventional trials and observational data. The research...
endocannabinoid system clinical research: cannabis for back pain
Clinical Takeaway In this phase 3 randomized controlled trial, a full-spectrum cannabis extract (VER-01) was evaluated in 820 adults with chronic low back pain over a 12-week double-blind period followed by longer-term...
Cannabinoid Clinical Trials: CBD and Cortical Excitability
Clinical Takeaway In a controlled crossover trial of healthy men, neither a low (30 mg) nor a high (700 mg) single dose of CBD directly altered cortical excitability compared to placebo. This...
Cannabinoid Clinical Trials: EEG Sleep Insomnia RCT
Clinical Takeaway In this pilot RCT of 20 adults with diagnosed insomnia disorder, a single oral dose of 10 mg THC combined with 200 mg CBD reduced total sleep time compared to...